Organ and Species Specificity in Chemical Carcinogenesis

Table of Contents

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   Book Overview
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   Chapter 1 The Nature of Organ Specificity in Chemical Carcinogenesis
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   Chapter 2 Species Differences in Response to Aromatic Amines
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   Chapter 3 Aflatoxin B 1 : Correlations of Patterns of Metabolism and DNA Modification with Biological Effects
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   Chapter 4 Species specificity in nitrosamine carcinogenesis.
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   Chapter 5 Organ specificity and interspecies differences in carcinogenesis by metabolism-independent alkylating agents.
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   Chapter 6 Organ and Species Specificity in Nickel Subsulfide Carcinogenesis
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   Chapter 7 Chemical Carcinogenesis Studies in Nonhuman Primates
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   Chapter 8 Organ specificity and tumor promotion.
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    Chapter 9 Skin tumor promotion: a comparative study of several stocks and strains of mice.
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    Chapter 10 The role of phorbol ester receptor binding in responses to promoters by mouse and human cells.
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    Chapter 11 Tissue and species specificity for phorbol ester receptors.
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    Chapter 12 Liver as a Model System for Analyzing Mechanisms of Tumor Initiation and Promotion
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    Chapter 13 Promotion of Urinary Bladder Carcinogenesis
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    Chapter 14 Species and Organ Differences in the Biotransformation of Chemical Carcinogens
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    Chapter 15 Species heterogeneity in the metabolic processing of benzo[a]pyrene.
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    Chapter 16 Endocrine Regulation of Xenobiotic Conjugation Enzymes
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    Chapter 17 Multiple Effects and Metabolism of α-Naphthoflavone in Induced and Uninduced Hepatic Microsomes
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    Chapter 18 Species Differences in the Activation of Benzo[a]pyrene in the Tracheal Epithelium of Rats and Hamsters
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    Chapter 19 Subcellular Metabolic Activation Systems: Their Utility and Limitations in Predicting Organ and Species Specific Carcinogenesis of Chemicals
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    Chapter 20 Cell-Mediated Mutagenesis, an Approach to Studying Organ Specificity of Chemical Carcinogens
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    Chapter 21 The activation of carcinogens by mammary cells: inter-organ and intra-organ specificity.
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    Chapter 22 Studies on the Mode of Action of Chemical Carcinogens in Cultured Mammalian Cells
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    Chapter 23 Comparison of the Sensitivity of Rodent and Human Cells to Chemical Carcinogens Using Viral Transformation, DNA Damage, and Cytotoxicity Assays
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    Chapter 24 Tissue-Specific Sister Chromatid Exchange Analyses in Mutagen-Carcinogen Exposed Animals
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    Chapter 25 Metabolism of Chemical Carcinogens by Tracheobronchial Tissues
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    Chapter 26 Introduction: DNA Damage and Repair
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    Chapter 27 DNA modification and repair in vivo: towards a biochemical basis of organ-specific carcinogenesis by methylating agents.
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    Chapter 28 Modification of DNA Repair Processes Induced by Nitrosamines
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    Chapter 29 Repair of Alkylated DNA by Cell Extracts from Various Organs and Species
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    Chapter 30 Time-dependent differences in the benzo[a]pyrene-DNA adducts present in cell cultures from different species.
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    Chapter 31 DNA Binding as a Probe for Metabolic Activation in Various Systems
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    Chapter 32 Cell specificity in DNA damage and repair.
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    Chapter 33 DNA Adduct Formation and Removal in N-Acetoxy-2-Acetylaminofluorene-Exposed Cultured Cells and in Organs from Rats Fed 2-Acetylaminofluorene
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    Chapter 34 Trans-Species and Trans-Tissue Extrapolation of Carcinogenicity Assays
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    Chapter 35 Carcinogenic Risk Assessment—The Consequences of Believing Models