Rational biosynthetic approaches for the production of new-to-nature compounds in fungi
Article in Fungal Genetics and Biology (February 2016)
Biocombinatorial Approaches for Drug Finding
Overview of attention for book
Table of Contents
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Altmetric BadgeBook Overview
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Altmetric BadgeChapter 1 Protein Domain Fold Similarity and Natural Product Structure as Guiding Principles for Compound Library Design
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Altmetric BadgeChapter 2 Sources of Polyketides and Non-Ribosomal Peptides
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Altmetric BadgeChapter 3 Polyketide Synthases: Mechanisms and Models
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Altmetric BadgeChapter 4 Functional and Structural Basis for Targeted Modification of Non-Ribosomal Peptlde Synthetases
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Altmetric BadgeChapter 5 Prerequisites for Combinatorial Biosynthesis: Evolution of Hybrid NRPS/PKS Gene Clusters
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Altmetric BadgeChapter 6 Engineering Glycosylation in Bioactive Compounds by Combinatorial Biosynthesis
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Altmetric BadgeChapter 7 Glycosyltransferases and Other Tailoring Enzymes as Tools for the Generation of Novel Compounds
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Altmetric BadgeChapter 8 Enzymatic Incorporation of Halogen Atoms into Natural Compounds
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Altmetric BadgeChapter 9 From Glucose to Antibiotics: What Controls the Fluxes?
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Altmetric BadgeChapter 10 Precursor-Directed Biosynthesis for the Generation of Novel Glycopetides
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Altmetric BadgeChapter 11 Tool-Box: Tailoring Enzymes for Bio-Combinatorial Lead Development and as Markers for Genome-Based Natural Product Lead Discovery
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Altmetric BadgeChapter 12 Natural Product Biosynthetic Assembly Lines: Prospects and Challenges for Reprogramming
Attention for Chapter 5:
Prerequisites for Combinatorial Biosynthesis: Evolution of Hybrid NRPS/PKS Gene Clusters