@guavapancake Many (most?) Spike copies are pre-primed by furin before leaving the source infected cell. This allows TMPRSS2/13/11 to prime them. Still needs ACE2 to trigger. https://t.co/SYH6AksZOQ https://t.co/EJ0F5cKZiN https://t.co/d1lCMOH7zA Etc
@liljurist @__ice9 @zzz_as_zzz @Valueinvestor41 @gstanchev @halvorz @lewistlc @pathdoc3 @88549439 @csentropy @AndyBiotech @julienpotet @Crashcart @Hongma123 @YinPD @assur153 @macroliter @VirusWhisperer @SpringerNature That’s not normally how the research l
@__ice9 @zzz_as_zzz @Valueinvestor41 @gstanchev @halvorz @liljurist @lewistlc @pathdoc3 @88549439 @csentropy @AndyBiotech @julienpotet @Crashcart @Hongma123 @YinPD @assur153 @macroliter @VirusWhisperer Worth reading, from this volume: https://t.co/LiFrfVw
@MackayIM «The proteolytic separation of the S1 and S2 subunits, termed priming, provides the CoV Spike protein with the structural flexibility required for the membrane fusion reaction.» https://t.co/CYaQml4OPb