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Chapter title |
Syngeneic Murine Metastasis Models: B16 Melanoma
|
---|---|
Chapter number | 10 |
Book title |
Metastasis Research Protocols
|
Published in |
Methods in molecular biology, January 2014
|
DOI | 10.1007/978-1-4614-8244-4_10 |
Pubmed ID | |
Book ISBNs |
978-1-4614-8243-7, 978-1-4614-8244-4
|
Authors |
Raffaella Giavazzi, Alessandra Decio |
Abstract |
The murine B16 melanoma is one of the most used tumor models, its application having been used to determine the mechanisms associated with the metastatic process and the development of anticancer therapies. The B16 melanoma was originally established by Fidler and collaborators as a tumor line metastasizing to the lung. Since that time a variety of cell lines have been derived, in vitro or in vivo, having different metastatic behaviors.The methods used to obtain artificial metastases to the lung through the intravenous injection of B16 melanoma cells and spontaneous metastasis formation following cancer cell growth in the footpad are described in this chapter. |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 57 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 30% |
Student > Ph. D. Student | 12 | 21% |
Student > Master | 8 | 14% |
Student > Bachelor | 2 | 4% |
Unspecified | 2 | 4% |
Other | 7 | 12% |
Unknown | 9 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 13 | 23% |
Agricultural and Biological Sciences | 11 | 19% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 12% |
Immunology and Microbiology | 7 | 12% |
Medicine and Dentistry | 3 | 5% |
Other | 5 | 9% |
Unknown | 11 | 19% |