The Biology of the Interferon System 1986

Table of Contents

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   Book Overview
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   Chapter 1 Amino Acid Residues Affecting Antiviral and Antiproliferative Activity in Interferon-α’s
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   Chapter 2 Differential Structures and Activities of Three IFN α 2 Variants Departing Only at Two Amino Acid Positions
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   Chapter 3 Selective Association of High Density Lipoprotein with Interferon Beta Serine
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   Chapter 4 Structure, Genetics and Function of Human β 2 Interferon
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   Chapter 5 Tailoring of Alpha Interferons Via In Vivo Recombination of the Genes
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   Chapter 6 A New Type of Interferon-Like Protein Produced by Peripheral Blood Mononuclear Cells Treated with Inhibitors of Transcription
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   Chapter 7 Apparent Auto-Inhibition of Murine Interferon-γ Due to a Serum Component
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   Chapter 8 Nuclear Localization of Internalized Interferons-β and -γ: A Role for Nuclear Receptors
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    Chapter 9 The 5′ End of the Human (2′–5′) Oligo a Synthetase Gene Contains Sequences Responsible for Transcriptional Activation by Interferon
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    Chapter 10 Expression and Preliminary Deletion Analysis of the 42 kDa 2–5A Synthetase Induced By Human Interferon
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    Chapter 11 The Double-Stranded RNA Dependent Protein Kinase from Human Cells
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    Chapter 12 Homologs to Mouse Mx Protein Induced by Interferon in Various Species
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    Chapter 13 Comparative Studies of the Genomic Structure of Two Human Interferon Induced Genes
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    Chapter 14 Characterization of Two New IFN-Induced Proteins
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    Chapter 15 Early Events in the Interaction of IFN-α with IFN-Sensitive and IFN-Resistant Daudi Cells
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    Chapter 16 Some Freshly EBV-Transformed B-Cell Lines Lack Functional IFN-Receptors
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    Chapter 17 Production of Antibodies Against the Murine IFN-γ Receptor
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    Chapter 18 Purification and Characterization of the Receptor for Human Interferon-γ
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    Chapter 19 Interferon Induction by Transfection of Sendai Virus C Gene cDNA
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    Chapter 20 Studies on the Expression of Spontaneous Interferon-Like Activity in Mouse Peritoneal Cells
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    Chapter 21 Cellular Factors Mediate Induction and Superinduction of the Human Interferon-β Gene
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    Chapter 22 Interferon Beta-2 is Constitutively Expressed in Human Monocytes
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    Chapter 23 Regulation of Human Fibroblast Growth by Autocrine Interferon-Beta
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    Chapter 24 Biological Activities of Human Interferon-β 2 Produced by cDNA Expression in Hamster Cells and Possible Autocrine Functions of this Cytokine-Induced IFN
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    Chapter 25 Overview of Long-Term IFN Effects on the Phenotype of Transformed and Tumor Cells
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    Chapter 26 Mechanisms for Anti-Invasive Effect of Interferon
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    Chapter 27 Comparison of Different Modes of Interferon Delivery by Tumor Specific Monoclonal Antibodies
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    Chapter 28 Characterization of Rat Monoclonal Antibodies to Mouse Interferon-α and -β
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    Chapter 29 Molecular and Cellular Biology of Tumor Necrosis Factor, Interferon-γ, and their Synergism
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    Chapter 30 Induction of 26kDa Protein mRNA in Human Cells Treated with Recombinant Human Tumour Necrosis Factor (rTNF)
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    Chapter 31 Interactions of Tumor Necrosis Factor, Interferon and Interleukin-1 in Cell Killing
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    Chapter 32 New Relationships Among IFN-Gamma, TNF and IL-1: Cellular and Biochemical Effects
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    Chapter 33 Antagonistic Effect of Type I Interferons on Human Macrophage Activation by Interferon-γ
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    Chapter 34 Gamma-Interferon Regulates Secretion of G-CSF in Human Monocytes on the Transcriptional Level
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    Chapter 35 Presence of Tumor Necrosis Factor and Lymphotoxin in Clinical Interferon Preparations Derived from Leukocytes
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    Chapter 36 Phenotype of γ-Interferon Producing Leukocytes
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    Chapter 37 Interferon Regulates Major Histocompatibility Class I Gene Expression through a 5′ Upstream Regulatory Region
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    Chapter 38 The Antiviral Effects of Tumor Necrosis Factors
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    Chapter 39 Interferon and Tumor Necrosis Factor Alter the Phospholipid Metabolism in Friend Leukemia Cell Tumors in Mice
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    Chapter 40 Antitumor Effects of Rat Rec.Ifn-γ in Rats Bearing Transplantable Rat Tumors
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    Chapter 41 Mechanisms of Anticancer Action of Interferons on Human Tumour Xenografts in Nude Mice
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    Chapter 42 IFN-Gamma Inhibits Osteosarcoma Xenografts in Nude Mice
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    Chapter 43 Transgenic Mice Carrying Exogenous Mouse Interferon Genes
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    Chapter 44 Studies on Interferon in the Bovine Species: Biological and Biochemical Effects
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    Chapter 45 Treatment of Malignant Endocrine Pancreatic Tumors with Human Leukocyte Interferon
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    Chapter 46 Efficacy of Alpha Interferons in Hairy Cell Leukemia (HCL) and Status of the Interferon System of Patients in Remission
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    Chapter 47 Wellferon R Efficacy in the Treatment of Hairy Cell Leukaemia (HCL)
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    Chapter 48 Detection of Urinary Enzyme Excretion as a Parameter of the Nephrotoxicity of Human Interferon Alpha-2b in Patients with Hairy Cell Leukemia (HCL)
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    Chapter 49 Interferon Alfa-N1 Wellferon R in Kaposi’s Sarcoma: Single Agent or Combination with Vinblastine
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    Chapter 50 Combined Interferon-Polychemotherapy versus Polychemotherapy in Multiple Myeloma: A Phase-III Study
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    Chapter 51 Recombinant Interferon Alpha (2A) Combined with Dacarbazine in Treatment of Metastatic Melanoma
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    Chapter 52 Intralesional Interferon-Alpha-Therapy in Advanced Malignant Melanoma
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    Chapter 53 Comparison of Clinical Toxicity of Natural Alpha and Recombinant Gamma Interferon. Results of Phase II Trials in Lung Cancer
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    Chapter 54 Antitumor Activity of Interferon- β Against Malignant Glioma in Combination with Chemotherapeutic Agent of Nitrosourea(ACNU)
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    Chapter 55 Interferon Alpha in the Treatment of Malignant Diseases: Sources, Doses, and Regimens
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    Chapter 56 Treatment of Various Malignancies with Recombinant IFN-γ
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    Chapter 57 Interferons and Interferon Inactivators in Aids, Arc and in Cancer Patients
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    Chapter 58 Overview:Clinical Trial with Natural and Recombinant Interferons in China
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    Chapter 59 Interferon Producing Capacity in Patients with Liver Disease, Diabetes Mellitus, Chronic Diseases and Malignant Diseases
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    Chapter 60 Early Treatment of the Common Cold with Intranasal Interferon Alpha-2a (Ro 22–8181): A Preliminary Pilot Study
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    Chapter 61 Long-Term Tolerance of Intranasal Recombinant Interferon-β SER in Man
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    Chapter 62 The Role of Alpha 2 Interferon in Combination with Acyclovir in Ophthalmic Zoster (an open pilot study)
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    Chapter 63 Production of a Partially Acid Labile Alpha Interferon in Cytomegalovirus Pneumonitis
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    Chapter 64 Randomized Controlled Trial of a Four Month Course of Recombinant Human Alpha Interferon in Patients with Chronic Type B Hepatitis
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    Chapter 65 Treatment of Chronic Hepatitis B Infection with Alpha (Lymphoblastoid) Interferon: Responses in Different Social And Ethnic Groups in Comparision to Adenine Arabinoside Monophosphate
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    Chapter 66 Interferon Alfa-n1 (Wellferon) ® in Severe Recurrent Genital Warts: Report of a Multi-Study Program
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    Chapter 67 Activity of Intralesional Interferon Alfa-2b in Viral and Malignant Skin Diseases
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    Chapter 68 Idiopathic Mixed Cryoglobulinemia: A New Therapeutic Approach with Alpha Interferon
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    Chapter 69 Treatment of Rheumatoid Arthritis (RA) with Interferon-Gamma (IFN-gamma): Results of Clinical Trials in Germany
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    Chapter 70 Interferon in Human Breast Cystic Disease
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    Chapter 71 Efficacy of Intrathecally Administered Natural Human Fibroblast Interferon as Treatment of Multiple Sclerosis
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    Chapter 72 A Study on the Efficacy of Recombinant HumanαD Type Interferon (rIFN-αD) in Treatment of Chronic Cervicitis
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    Chapter 73 Presence and Possible Role of Interferons in Psoriasis
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    Chapter 74 The Components of the Interferon System in SLE and Psoriasis
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    Chapter 75 Pharmacokinetics of [ 123 I]-Interferon (IFN) Alpha-A
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    Chapter 76 2′5′ A Synthetase Activity is Induced by a Factor Excreted in Heat-Shocked Cells. Comparison of this Factor with IFN
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    Chapter 77 Mapping the Action of Interferon on Primate Brain
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    Chapter 78 Chemical and Biological Characterization of Natural Human Lymphoblastoid Interferon Alphas