| Chapter title |
Bluegenics: Bioactive Natural Products of Medicinal Relevance and Approaches to Their Diversification
|
|---|---|
| Chapter number | 5 |
| Book title |
Blue Biotechnology
|
| Published in |
Progress in molecular and subcellular biology, January 2017
|
| DOI | 10.1007/978-3-319-51284-6_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-951282-2, 978-3-31-951284-6
|
| Authors |
Joseph S. Zarins-Tutt, Emily R. Abraham, Christopher S. Bailey, Rebecca J. M. Goss |
| Abstract |
Nature provides a valuable resource of medicinally relevant compounds, with many antimicrobial and antitumor agents entering clinical trials being derived from natural products. The generation of analogues of these bioactive natural products is important in order to gain a greater understanding of structure activity relationships; probing the mechanism of action, as well as to optimise the natural product's bioactivity and bioavailability. This chapter critically examines different approaches to generating natural products and their analogues, exploring the way in which synthetic and biosynthetic approaches may be blended together to enable expeditious access to new designer natural products. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 30% |
| Student > Bachelor | 3 | 30% |
| Professor > Associate Professor | 1 | 10% |
| Researcher | 1 | 10% |
| Unknown | 2 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 3 | 30% |
| Chemistry | 2 | 20% |
| Biochemistry, Genetics and Molecular Biology | 1 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
| Unknown | 3 | 30% |