Chapter title |
Management of Lung Cancer in the Elderly
|
---|---|
Chapter number | 12 |
Book title |
Lung Cancer
|
Published in |
Cancer treatment and research, January 2016
|
DOI | 10.1007/978-3-319-40389-2_12 |
Pubmed ID | |
Book ISBNs |
978-3-31-940387-8, 978-3-31-940389-2
|
Authors |
Archana Rao, Namita Sharma, Ajeet Gajra, Rao, Archana, Sharma, Namita, Gajra, Ajeet |
Abstract |
Lung cancer is the leading cause of cancer-associated mortality in the USA. The median age at diagnosis of lung cancer is 70 years, and thus, about one-half of patients with lung cancer fall into the elderly subgroup. There is dearth of high level of evidence regarding the management of lung cancer in the elderly in the three broad stages of the disease including early-stage, locally advanced, and metastatic disease. A major reason for the lack of evidence is the underrepresentation of elderly in prospective randomized clinical trials. Due to the typical decline in physical and physiologic function associated with aging, most elderly do not meet the stringent eligibility criteria set forth in age-unselected clinical trials. In addition to performance status, ideally, comorbidity, cognitive, and psychological function, polypharmacy, social support, and patient preferences should be taken into account before applying prevailing treatment paradigms often derived in younger, healthier patients to the care of the elderly patient with lung cancer. The purpose of this chapter was to review the existing evidence of management of early-stage, locally advanced disease, and metastatic lung cancer in the elderly. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 1% |
United States | 1 | 1% |
Unknown | 85 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 15 | 17% |
Student > Ph. D. Student | 14 | 16% |
Student > Bachelor | 9 | 10% |
Researcher | 8 | 9% |
Student > Doctoral Student | 6 | 7% |
Other | 19 | 22% |
Unknown | 16 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 34 | 39% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 10% |
Nursing and Health Professions | 5 | 6% |
Psychology | 5 | 6% |
Agricultural and Biological Sciences | 4 | 5% |
Other | 12 | 14% |
Unknown | 18 | 21% |