Computational Intelligence Methods for Bioinformatics and Biostatistics

Chapter 1 Coarse-Grained Modeling of the HIV–1 Protease Binding Mechanisms: I. Targeting Structural Flexibility of the Protease Flaps and Implications for Drug Design

Chapter 2 Coarse-Grained Modeling of the HIV–1 Protease Binding Mechanisms: II. Folding Inhibition

Chapter 3 Unsupervised Stability-Based Ensembles to Discover Reliable Structures in Complex Bio-molecular Data

Chapter 4 Comparative In Silico Evaluation of MYB Transcription Factors in Eucalyptus, Sugarcane and Rice Transcriptomes

Chapter 6 In Silico Evaluation of Osmoprotectants in Eucalyptus Transcriptome

Chapter 7 Mining Association Rule Bases from Integrated Genomic Data and Annotations

Chapter 8 Stability and Performances in Biclustering Algorithms

Chapter 9 Splice Site Prediction Using Artificial Neural Networks

Chapter 10 Interval Length Analysis in Multi Layer Model

Chapter 11 A Multivariate Algorithm for Gene Selection Based on the Nearest Neighbor Probability

Chapter 12 Control of Cellular Glycolysis by Perturbations in the Glucose Influx

Chapter 13 Curating a Large-Scale Regulatory Network by Evaluating Its Consistency with Expression Datasets

Chapter 14 Spatial Clustering of Molecular Dynamics Trajectories in Protein Unfolding Simulations

Chapter 15 Clustering Bacteria Species Using Neural Gas: Preliminary Study

Chapter 16 A New Linear Initialization in SOM for Biomolecular Data

Chapter 17 3D Volume Reconstruction and Biometric Analysis of Fetal Brain from MR Images

Chapter 18 Searching for Glycomics Role in Stem Cell Development

Chapter 19 A New Protein Representation Based on Fragment Contacts: Towards an Improvement of Contact Maps Predictions

Chapter 20 Analysis of Kernel Based Protein Classification Strategies Using Pairwise Sequence Alignment Measures

Chapter 21 Topology Preserving Neural Networks for Peptide Design in Drug Discovery

Chapter 22 A Machine Learning Approach to Mass Spectra Classification with Unsupervised Feature Selection

Chapter 23 Liver i-Biopsy TM and the Corresponding Intelligent Fibrosis Scoring Systems: i-Metavir F and i-Ishak F

Chapter 24 An Extension of the TIGR M4 Suite to Preprocess and Visualize Affymetrix Binary Files

Chapter 25 A Supervised Learning Technique and Its Applications to Computational Biology

Chapter 26 A Visualization ToolKit Based Application for Representing Macromolecular Surfaces