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Drug Design and Discovery

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Cover of 'Drug Design and Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 Virtual Screening for Lead Discovery
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    Chapter 2 Computer-Aided Drug Discovery and Development
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    Chapter 3 Using Active Site Mapping and Receptor-Based Pharmacophore Tools: Prelude to Docking and De Novo/Fragment-Based Ligand Design
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    Chapter 4 Methods for Evaluation of Structural and Biological Properties of Antiinvasive Natural Products
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    Chapter 5 Solid-Phase Peptide Synthesis Using Microwave Irradiation
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    Chapter 6 Fluorescent and lanthanide labeling for ligand screens, assays, and imaging.
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    Chapter 7 DNA-Directed Assembly Microarray for Protein and Small Molecule Inhibitor Screening
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    Chapter 8 Selection of Peptide Ligands for Human Placental Transcytosis Systems Using In Vitro Phage Display
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    Chapter 9 Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability.
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    Chapter 10 Imaging NF-κB Signaling in Mice for Screening Anticancer Drugs
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    Chapter 11 Evaluation of Anticancer Agents Using Flow Cytometry Analysis of Cancer Stem Cells
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    Chapter 12 Chemical Screening with Zebrafish Embryos
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    Chapter 13 iTRAQ ™ Labeling Coupled with LC-MALDI Mass Spectrometry for Monitoring Temporal Response of Colorectal Cancer Cells to Butyrate Treatment
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    Chapter 14 Heterotypic Cell Adhesion Assay for the Study of Cell Adhesion Inhibition
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    Chapter 15 Evaluation of Antibacterial Activity of Proteins and Peptides Using a Specific Animal Model for Wound Healing
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    Chapter 16 In Vitro Immunogenicity Risk Assessment of Therapeutic Proteins in Preclinical Setting
Attention for Chapter 9: Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability.
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