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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

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Cover of 'Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy'

Table of Contents

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    Book Overview
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    Chapter 1 Platinum DNA Chemistry
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    Chapter 2 New Insights About the Interaction of Cisplatinum with Intracellular Components
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    Chapter 3 Modelling Platinum-DNA Interactions
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    Chapter 4 From the Modelization of DNA Platination to the Conception of New Drugs
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    Chapter 5 Cis -Diammineplatinum(II) Complexes Tethered to DNA-Affinic Ligands: Antitumour Activity and DNA-Binding Properties
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    Chapter 6 Complexes of Peptides and Related Molecules with Diammineplatinum (II) as Models for Platinum-Protein Interactions
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    Chapter 7 Reactivity of DNA and cis -Diamminedichloroplatinumul(II) in the Presence of Intercalating Agents
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    Chapter 8 Structurally Novel Platinum Antitumor Compounds
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    Chapter 9 Synthesis and Reactions of a New Class of Orally Active Pt(IV) Antitumor Complexes
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    Chapter 10 Pt-DNA Interactions: Oligonucleotide Models
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    Chapter 11 New Approaches to the Design of Platinum Antitumor Agents
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    Chapter 12 Developmental Approach to Prepare New Types of Antitumor Platinum Complexes with Dual Function
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    Chapter 13 Synthesis and Antitumour Activity of Some Novel Platinum(II) Organoamides and Organometallics
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    Chapter 14 Role of Membrane Ion Transport in Cisplatin Accumulation
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    Chapter 15 Enhancement of the Antiproliferative Effect of cis-Diamminedichloroplatinum (II) and Other Antitumor Agents by Inhibitors of Enzymes Involved in Growth Factor Signal-Transduction
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    Chapter 16 Signal Transduction Pathway Regulation of DDP Sensitivity
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    Chapter 17 The Role of Platinum-DNA Lesions in the Inhibition of DNA Replication
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    Chapter 18 Activation of a Genetic Program for Cell Death
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    Chapter 19 Molecular Aspects of Repair and Mutagenesis of cis -Platinum-Induced Lesions
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    Chapter 20 Isolation of a Gene Associated with Resistance to Cisplatin
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    Chapter 21 Repair of Damaged DNA In Vitro by Extracts from Human Cell Lines
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    Chapter 22 Gene Specific Damage and Repair of Platinum Adducts and Crosslinks
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    Chapter 23 A Protein from Mammalian Cells that Recognizes Platinated DNA
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    Chapter 24 Sensitization of Resistant Human Tumor Cells to Cisplatin or Carboplatin by Inhibitors of DNA Excision Repair
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    Chapter 25 Carrier Ligand Effects in Platinum Resistant Cell Lines
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    Chapter 26 Immunocytochemical Analysis of Platinum-DNA Adducts
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    Chapter 27 Strategies for Increasing the Efficacy of and Overcoming Resistance to Platinum Complexes In Vivo
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    Chapter 28 The Role of the c- fos Oncogene in Cisplatin Resistance
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    Chapter 29 Metallothioneins and Cisplatin Resistance
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    Chapter 30 A New Membrane Protein Associated with Resistance to cis-Platinum and Methotrexate
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    Chapter 31 Pharmacokinetics of Carboplatin in Children and the Development of a Paediatric Dose Equation
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    Chapter 32 Clinical Studies with Cisplatin Analogues, 254-S, DWA2114R and NK121
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    Chapter 33 Clinical and Pharmacokinetic Studies on the New Platinum Complex Zeniplatin (CL286,558)
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    Chapter 34 Oxalatoplatinum (I-OHP): Experimental and Clinical Studies
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    Chapter 35 Pharmacological Studies with New Liposome-Entrapped Cisplatin Derivatives
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    Chapter 36 Ammine/Amine Platinum IV Dicarboxylates: A Novel Class of Complexes Which Circumvent Intrinsic Cisplatin Resistance
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    Chapter 37 Dose Intensity Analysis May Help Resolve Issues in Chemotherapy with Platinum Compounds
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    Chapter 38 Cisplatin Dose-intensity in Testicular Cancer Treatment: Analysis of a Randomized Clinical Trial
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    Chapter 39 Phase I/II Study to Further Escalate the Dose of Carboplatin in Combination with GM-CSF in the Treatment of Refractory Ovarian Cancer
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    Chapter 40 High-Dose Carboplatin with Peripheral Blood Stem Cell and Growth Factor Support
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    Chapter 41 Pharmacologic, Pre-clinical and Clinical Investigations of the Cisplatin/Taxol Combination
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    Chapter 42 Phase I Trials with Ormaplatin (Tetraplatin)
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    Chapter 43 Intraperitoneal Cisplatin and Carboplatin in the Management of Ovarian Cancer
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    Chapter 44 Radiotherapy Combined with Daily or Weekly cis-Diammine Dichloroplatinum (II) in Inoperable Non-Metastasized Non-Small Cell Lung Cancer: A Toxicity Report of the Randomized Phase III Study of the EORTC Lung Cancer Cooperative and Radiotherapy Cooperative Groups
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    Chapter 45 Optimizing Dose-Intensity: Combining Carboplatin with Cisplatin
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    Chapter 46 High Dose Cisplatin: Modulation of Toxicity
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    Chapter 47 Probenecid and Diethyldithiocarbamate as Modifiers of Cisplatin Toxicity
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    Chapter 48 ORG 2766 in the Prevention of Cisplatin Neuropathy
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    Chapter 49 WR-2721 (Ethyol®): Reduction in Toxicity of Anticancer Therapy without Loss of Efficacy
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    Chapter 50 High-Dose Cisplatin with Glutathione Protection in Gynecologic Malignancies
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    Chapter 51 Improved Efficacy of “Two-route Chemotherapy” Using Cisplatin and its Antidote, Sodium Thiosulfate, in Combination with Angiotensin II
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Title
Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
Published by
Springer US, November 2013
DOI 10.1007/978-1-4899-0738-7
ISBNs
978-1-4899-0740-0, 978-1-4899-0738-7
Editors

Howell, Stephen B.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 31 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 22%
Student > Ph. D. Student 7 22%
Student > Doctoral Student 3 9%
Researcher 3 9%
Student > Master 2 6%
Other 3 9%
Unknown 7 22%
Readers by discipline Count As %
Chemistry 10 31%
Agricultural and Biological Sciences 4 13%
Engineering 3 9%
Physics and Astronomy 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 2 6%
Unknown 10 31%