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Prion Diseases

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Cover of 'Prion Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 Prions: from neurografts to neuroinvasion
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    Chapter 2 Follicular dendritic cells in scrapie pathogenesis
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    Chapter 3 Cellular and sub-cellular localisation of PrP in the lymphoreticular system of mice and sheep
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    Chapter 4 Pharmacological manipulation of early PrPres accumulation in the spleen of scrapie-infected mice
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    Chapter 5 Pathogenesis of natural scrapie in sheep.
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    Chapter 6 Detection of cattle-derived BSE prions using transgenic mice overexpressing bovine PrP c
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    Chapter 7 Analyzing the influence of PrP primary structure on prion pathogenesis in transgenic mice
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    Chapter 8 Prion Diseases
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    Chapter 9 A transgenic model of a familial prion disease
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    Chapter 10 Transgenic models of prion disease
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    Chapter 11 Surveillance of BSE
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    Chapter 12 Histopathology and immunohistochemistry of human transmissible spongiform encephalopathies (TSEs)
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    Chapter 13 Pathology of variant Creutzfeldt-Jakob disease
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    Chapter 14 Clinical and differential diagnosis of Creutzfeldt-Jakob disease
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    Chapter 15 Putting prions into focus: application of single molecule detection to the diagnosis of prion diseases
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    Chapter 16 Detection of PrP Sc in subclinical BSE with the paraffin-embedded tissue (PET) blot
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    Chapter 17 Prion Diseases
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    Chapter 18 Application of Prionics Western blotting procedure to screen for BSE in cattle regularly slaughtered at Swiss abattoirs
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    Chapter 19 Specific determination of the proteinase K-resistant form of the prion protein using two-site immunometric assays. Application to the post-mortem diagnosis of BSE
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    Chapter 20 PrP Sc typing by N-terminal sequencing and mass spectrometry
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    Chapter 21 Characterization of BSE and scrapie strains/isolates
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    Chapter 22 Quantitative traits of prion strains are enciphered in the conformation of the prion protein
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    Chapter 23 Function of PrP C as a copper-binding protein at the synapse
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    Chapter 24 The prion protein globular domain and disease-related mutants studied by molecular dynamics simulations
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    Chapter 25 Neurotoxicity but not infectivity of prion proteins can be induced reversibly in vitro
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    Chapter 26 Inhibition of formation of protease-resistant prion protein by Trypan Blue, Sirius Red and other Congo Red analogs
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    Chapter 27 The use of monoclonal antibody epitopes for tagging PrP in conversion experiments
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Title
Prion Diseases
Published by
Springer Vienna, December 2012
DOI 10.1007/978-3-7091-6308-5
ISBNs
978-3-21-183529-6, 978-3-70-916308-5, 978-3-21-183530-2
Editors

Groschup, Martin H., Kretzschmar, Hans A.

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