Ribozymes

Chapter 1 Introduction

Chapter 2 Characterization of Hammerhead Ribozyme Reactions

Chapter 3 Mechanistic Analysis of the Hepatitis Delta Virus (HDV) Ribozyme: Methods for RNA Preparation, Structure Mapping, Solvent Isotope Effects, and Co-transcriptional Cleavage

Chapter 4 Kinetic Characterization of Hairpin Ribozyme Variants

Chapter 5 Characterization of RNase P RNA Activity

Chapter 6 Group I Intron Ribozymes

Chapter 7 Kinetic Characterization of Group II Intron Folding and Splicing

Chapter 8 Mechanism and Distribution of glmS Ribozymes

Chapter 9 Structure-Based Search and In Vitro Analysis of Self-Cleaving Ribozymes

Chapter 10 Discovery of RNA Motifs Using a Computational Pipeline that Allows Insertions in Paired Regions and Filtering of Candidate Sequences.

Chapter 11 Crystallographic Analysis of Small Ribozymes and Riboswitches

Chapter 12 Functional Dynamics of RNA Ribozymes Studied by NMR Spectroscopy

Chapter 13 Ribozymes

Chapter 14 Ribozymes

Chapter 15 Single Molecule FRET Characterization of Large Ribozyme Folding

Chapter 16 Metal Ion–RNA Interactions Studied via Multinuclear NMR

Chapter 17 Analysis of Catalytic RNA Structure and Function by Nucleotide Analog Interference Mapping

Chapter 18 In Vitro Selection of Metal Ion-Selective DNAzymes

Chapter 19 Selecting Allosteric Ribozymes

Chapter 20 Screening Effective Target Sites on mRNA: A Ribozyme Library Approach

Chapter 21 A Computational Approach to Predict Suitable Target Sites for trans -Acting Minimal Hammerhead Ribozymes

Chapter 22 Targeting mRNAs by Engineered Sequence-Specific RNase P Ribozymes

Chapter 23 Target-Induced SOFA-HDV Ribozyme

Chapter 24 Ribozyme-Mediated Trans Insertion-Splicing into Target RNAs

Chapter 25 Developing Fluorogenic RNA-Cleaving DNAzymes for Biosensing Applications

Chapter 26 Ribozymes

Chapter 28 In vivo screening of ligand-dependent hammerhead ribozymes.

Chapter 29 Flexizymes as a tRNA Acylation Tool Facilitating Genetic Code Reprogramming