Diversification in Toxicology — Man and Environment

Table of Contents

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   Book Overview
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   Chapter 1 Molecular Basis of Halothane Hepatitis
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   Chapter 2 Receptor -Mediated Toxicity
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   Chapter 3 Animal Burdens versus Human Benefits — How Should the Ethical Limits be Drawn for Use of Animals as Models in Toxicology?
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   Chapter 4 Behavior of Laboratory Animals under Unnatural Conditions
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   Chapter 5 The Impact of Stress and Discomfort on Experimental Outcome
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   Chapter 6 Priorities in the Development of Alternative Methodologies in the Pharmaceutical Industry
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   Chapter 7 Development and Strategic Use of Alternative Tests in Assessing the Hazard of Chemicals
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   Chapter 8 Soil Ecotoxicological Risk Assessment: How to Find Avenues in a Pitch Dark Labyrinth
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    Chapter 9 Monitoring and Risk Assessment for Endocrine Disruptors in the Aquatic Environment: A Biomarker Approach
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    Chapter 10 Developmental and Reproductive Toxicity of Persistent Environmental Pollutants
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    Chapter 11 Effects of the In Vitro Chemical Environment During Early Embryogenesis on Subsequent Development
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    Chapter 12 Influence of Hormones and Hormone Antagonists on Sexual Differentiation of the Brain
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    Chapter 13 Reproductive effects from oestrogen activity in polluted water.
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    Chapter 14 Effects of Chemical-Induced DNA Damage on Male Germ Cells
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    Chapter 15 Animal Locomotor Behaviour as a Health Biomarker of Chemical Stress
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    Chapter 16 Markers of Exposure to Aromatic Amines and Nitro-PAH
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    Chapter 17 Hematological and Biochemical Parameters in Pollution-Exposed Mice
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    Chapter 18 Detection of Low Levels of DNA Damage Arising from Exposure of Humans to Chemical Carcinogens
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    Chapter 19 Natural Antioxidants in Chemoprevention
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    Chapter 20 Development of In Vitro Models for Cellular and Molecular Studies in Toxicology and Chemoprevention
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    Chapter 21 Bioavailability and Health Effects of Dietary Flavonols in Man
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    Chapter 22 Epidemiological Studies on Antioxidants, Lipid Peroxidation and Atherosclerosis
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    Chapter 23 Regulatory immunotoxicology--the scientist's point of view: an introduction.
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    Chapter 24 Contact and Respiratory Allergy: A Regulatory Perspective
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    Chapter 25 Immunotoxicology: Extrapolation from Animal to Man — Estimation of the Immunotoxicologic Risk Associated with TBTO Exposure
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    Chapter 26 Regulating Immunotoxicity Evaluation: Issues and Needs
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    Chapter 27 Biomarkers in Metabolic Subtyping — Relevance for Environmental Cancer Control
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    Chapter 28 Assessment of Animal Tumour Promotion Data for the Human Situation
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    Chapter 29 Use of Transgenic Mutational Test Systems in Risk Assessment of Carcinogens
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    Chapter 30 Assessing Toxicological Impacts in Life Cycle Assessment
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    Chapter 31 Risk Assessment for Complex Chemical Exposure in Aquatic Systems: The Problem of Estimating Interactive Effects
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    Chapter 32 Exposure of Humans to Complex Chemical Mixtures: Hazard Identification and Risk Assessment
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    Chapter 33 Peroxisome Proliferator-Activated Receptor-alpha and the Pleiotropic Responses to Peroxisome Proliferators
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    Chapter 34 Excitotoxicity in the Brain
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    Chapter 35 Variability in the Response of Daphnia Clones to Toxic Substances: Are Safety Margins Being Compromised?
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    Chapter 36 Sources and Implications of Variability in Sensitivity to Chemicals for Ecotoxicological Risk Assessment
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    Chapter 37 Polymorphism in Glutathione S-Transferase Loci as a Risk Factor for Common Cancers
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    Chapter 38 Population Responses to Contaminant Exposure in Marine Animals: Influences of Genetic Diversity Measured as Allozyme Polymorphism
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    Chapter 39 The use of transgenic animals to assess the role of metabolism in target organ toxicity.
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    Chapter 40 Extrahepatic Cytochrome P450: Role in In Situ Toxicity and Cell-Specific Hormone Sensitivity
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    Chapter 41 Expression of xenobiotic-metabolizing cytochrome P450s in human pulmonary tissues.
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    Chapter 42 Comparison of GST Theta Activity in Liver and Kidney of Four Species
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    Chapter 43 Haloalkene Conjugate Toxicity: The Role of Human Renal Cysteine Conjugate C-S Lyase