Chapter 1 Causality in Medicine

Chapter 2 The Evolution of the Biomedical Paradigm in Oncology: Implications for Cancer Therapy

Chapter 3 Anticancer Drug Discovery and Development

Chapter 4 Beyond VEGF: Targeting Tumor Growth and Angiogenesis via Alternative Mechanisms

Chapter 5 Aurora Kinases and Their Inhibitors: More Than One Target and One Drug

Chapter 6 Signalling Pathways and Adhesion Molecules as Targets for Antiangiogenesis Therapy in Tumors

Chapter 7 Targeted Therapies in Cancer

Chapter 8 Anticancer Cell Therapy with TRAIL-Armed CD34 + Progenitor Cells

Chapter 9 Linking inflammation reactions to cancer: novel targets for therapeutic strategies.

Chapter 10 Clinical Development of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors: What Lessons Have We Learned?

Chapter 11 GIST As the Model of Paradigm Shift Towards Targeted Therapy of Solid Tumors: Update and Perspective on Trial Design

Chapter 12 Monoclonal Antibodies in the Treatment of Malignant Lymphomas