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Molecular, Clinical and Environmental Toxicology

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Cover of 'Molecular, Clinical and Environmental Toxicology'

Table of Contents

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    Book Overview
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    Chapter 1 Historical milestones and discoveries that shaped the toxicology sciences
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    Chapter 2 Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
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    Chapter 3 The role of biotransformation and bioactivation in toxicity.
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    Chapter 4 Genotoxicity: damage to DNA and its consequences.
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    Chapter 5 Role of DNA repair in the protection against genotoxic stress
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    Chapter 6 On the impact of the molecule structure in chemical carcinogenesis
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    Chapter 7 Chemical induced alterations in p53 signaling
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    Chapter 8 Molecular pathways involved in cell death after chemically induced DNA damage
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    Chapter 9 The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways
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    Chapter 10 Mapping the epigenome — impact for toxicology
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    Chapter 11 Molecular, Clinical and Environmental Toxicology
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    Chapter 12 Toxicogenomics: transcription profiling for toxicology assessment
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    Chapter 13 The role of toxicoproteomics in assessing organ specific toxicity
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    Chapter 14 High-throughput screening for analysis of in vitro toxicity
Attention for Chapter 2: Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
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