Drug Absorption Studies

Table of Contents

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   Book Overview
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   Chapter 1 Models for Skin Absorption and Skin Toxicity Testing
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   Chapter 2 Models of the Small Intestine
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   Chapter 3 Drug Absorption from the Colon In Situ
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   Chapter 4 In Vivo and In Vitro Models for Assessing Drug Absorption Across the Buccal Mucosa
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   Chapter 5 In Situ and Ex Vivo Nasal Models for Preclinical Drug Development Studies
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   Chapter 6 The Isolated Perfused Lung for Drug Absorption Studies
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   Chapter 7 In Vitro Models for Investigations of Buccal Drug Permeation and Metabolism
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   Chapter 8 In Vitro Screening Models to Assess Intestinal Drug Absorption and Metabolism
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    Chapter 9 In Vitro Cellular Models for Nasal Drug Absorption Studies
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    Chapter 10 In Vitro Models of the Tracheo-Bronchial Epithelium
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    Chapter 11 In Vitro Models of the Alveolar Epithelial Barrier
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    Chapter 12 Cell Culture Models of the Corneal Epithelium and Reconstructed Cornea Equivalents for In Vitro Drug Absorption Studies
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    Chapter 13 The Conjunctival Barrier in Ocular Drug Delivery
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    Chapter 14 Inner Blood—Retinal Barrier: Transport Biology and Methodology
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    Chapter 15 Regulation of Paracellular Permeability in Low-Resistance Human Vaginal-Cervical Epithelia
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    Chapter 16 In Vitro Models and Multidrug Resistance Mechanisms of the Placental Barrier
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    Chapter 17 In Vitro Models to Study Blood-Brain Barrier Function
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    Chapter 18 High-Throughput Screening Using Caco-2 Cell and PAMPA Systems
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    Chapter 19 Instrumented In Vitro Approaches to Assess Epithelial Permeability of Drugs from Pharmaceutical Formulations
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    Chapter 20 Modeling Transdermal Absorption
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    Chapter 21 Physiologically Based in Silico Models for the Prediction of Oral Drug Absorption
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    Chapter 22 In Silico Modeling for Blood—Brain Barrier Permeability Predictions
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    Chapter 23 Impact of Drug Transport Proteins
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    Chapter 24 Cloning and Functional Heterologous Expression of Transporters
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    Chapter 25 The Pharmacology of Caveolae
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    Chapter 26 Immortalization Strategies for Epithelial Cells in Primary Culture
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    Chapter 27 Binding-Uptake Studies and Cellular Targeting
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    Chapter 28 Drug Permeability Studies in Regulatory Biowaiver Applications