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Cysteine Proteases of Pathogenic Organisms

Overview of attention for book
Cover of 'Cysteine Proteases of Pathogenic Organisms'

Table of Contents

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    Book Overview
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    Chapter 1 Papain-Like Proteases of Staphylococcus aureus
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    Chapter 2 The Lysine-Specific Gingipain of Porphyromonas gingivalis
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    Chapter 3 Falcipains and Other Cysteine Proteases of Malaria Parasites
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    Chapter 4 Cathepsin Proteases in Toxoplasma gondii
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    Chapter 5 Entamoeba histolytica Cathepsin-Like Enzymes
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    Chapter 6 Cysteine Peptidases of Kinetoplastid Parasites
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    Chapter 7 Cruzain
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    Chapter 8 The Phylogeny, Structure and Function of Trematode Cysteine Proteases, with Particular Emphasis on the Fasciola hepatica Cathepsin L Family
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    Chapter 9 Cathepsins B1 and B2 of Trichobilharzia SPP., Bird Schistosomes Causing Cercarial Dermatitis
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    Chapter 10 Proteases in Blood-Feeding Nematodes and Their Potential as Vaccine Candidates
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    Chapter 11 Cysteine Proteases from Bloodfeeding Arthropod Ectoparasites
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    Chapter 12 How Pathogen-Derived Cysteine Proteases Modulate Host Immune Responses
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    Chapter 13 Cysteine Proteases of Pathogenic Organisms
Attention for Chapter 6: Cysteine Peptidases of Kinetoplastid Parasites
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Chapter title
Cysteine Peptidases of Kinetoplastid Parasites
Chapter number 6
Book title
Cysteine Proteases of Pathogenic Organisms
Published in
Advances in experimental medicine and biology, February 2016
DOI 10.1007/978-1-4419-8414-2_6
Pubmed ID
21660660
Book ISBNs
978-1-4419-8413-5, 978-1-4419-8414-2
Authors

Conor R. Caffrey, Ana-Paula Lima, Dietmar Steverding, Caffrey, Conor R., Lima, Ana-Paula, Steverding, Dietmar

Abstract

We review Clan CA Family C1 peptidases of kinetoplastid parasites (Trypanosoma and Leishmania) with respect to biochemical and genetic diversity, genomic organization and stage-specificity and control of expression. We discuss their contributions to parasite metabolism, virulence and pathogenesis and modulation of the host's immune response. Their applications as vaccine candidates and diagnostic markers as well as their chemical and genetic validation as drug targets are also summarized.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
France 1 3%
Brazil 1 3%
Unknown 32 91%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 20%
Student > Ph. D. Student 7 20%
Researcher 5 14%
Student > Bachelor 4 11%
Professor > Associate Professor 2 6%
Other 4 11%
Unknown 6 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 23%
Biochemistry, Genetics and Molecular Biology 5 14%
Pharmacology, Toxicology and Pharmaceutical Science 4 11%
Chemistry 4 11%
Medicine and Dentistry 4 11%
Other 4 11%
Unknown 6 17%

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