| Chapter title |
A new category of psychotropic drugs: neuroactive lipids as exemplified by ethyl eicosapentaenoate (E-E).
|
|---|---|
| Chapter number | 6 |
| Book title |
Progress in Drug Research
|
| Published in |
Fortschritte der Arzneimittelforschung Progress in drug research Progrès des recherches pharmaceutiques, January 2002
|
| DOI | 10.1007/978-3-0348-8171-5_6 |
| Pubmed ID | |
| Book ISBNs |
978-3-03-489464-7, 978-3-03-488171-5
|
| Authors |
David F. Horrobin, Horrobin, David F. |
| Abstract |
New treatments for psychiatric disorders are urgently required. Recent reviews show that there have been no improvements in efficacy of drugs for either affective disorders or schizophrenia since the first compounds were introduced over 40 years ago. Neuroactive lipids represent an entirely novel class of psychotropic compounds. Ethyl eicosapentaenoate is the first example of this group. Placebo-controlled studies have found it to be effective in depression, in treatment-unresponsive schizophrenia and in tardive dyskinesia. It is extremely well tolerated with none of the usual side-effects of either antidepressants or neuroleptics. It probably works by modulating postreceptor signal transduction processes. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 3 | 18% |
| Researcher | 3 | 18% |
| Professor | 2 | 12% |
| Student > Ph. D. Student | 2 | 12% |
| Student > Doctoral Student | 1 | 6% |
| Other | 3 | 18% |
| Unknown | 3 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 29% |
| Psychology | 4 | 24% |
| Neuroscience | 2 | 12% |
| Agricultural and Biological Sciences | 1 | 6% |
| Unspecified | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 4 | 24% |