Purine and Pyrimidine Metabolism in Man V

Table of Contents

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   Book Overview
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   Chapter 1 Adenosine Receptors on Human T Lymphocytes and Human Thymocytes
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   Chapter 2 Adenosine Receptors on Human Lymphocytes
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   Chapter 3 Inhibition of Mast Cell Mediator Release by 5-Amino-4-Imidazolecarboxamide Riboside
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   Chapter 4 Purine Metabolism by Guinea-Pig Ileum
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   Chapter 5 Suppression by 5′-Methylthioadenosine of Histamine or Leukotriene-Induced Contraction in Isolated Guinea Pig Tracheal Rings
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   Chapter 6 Adenosine Receptors on Human Basophils and Lung Mast Cells
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   Chapter 7 Hypoxanthine Uptake by Isolated Brain Microvessels
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   Chapter 8 Morphine: Sites of Action in Guanosine Nucleoside Pathway
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    Chapter 9 Purine and monoamine metabolites in cerebrospinal fluid.
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    Chapter 10 Characteristics of High Affinity and Low Affinity Adenosine Binding Sites in Human Cerebral Cortex
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    Chapter 11 Hypoxanthine Transport Through Human Erythrocyte Membranes
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    Chapter 12 Regulatory Aspects of Hypoxanthine Uptake by Human Erythrocytes
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    Chapter 13 Mutant mouse cells with nitrobenzylthioinosine-insensitive nucleoside transport functions.
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    Chapter 14 Carrier Mediated Uptake of Deoxyguanosine in Rat Liver Mitochondria
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    Chapter 15 Mechanism of Thymineless Death
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    Chapter 16 Enhancement of Methotrexate Cytotoxicity by Uracil Analogues that Inhibit Deoxyuridine Triphosphate Nucleotidohydrolase (dUTPase) Activity
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    Chapter 17 Influence of Methotrexate on Purine and Pyrimidine Pools and on Cell Phase Distribution of Cultured Human Lymphoblasts
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    Chapter 18 Modulation of Cytotoxicity and Metabolism of 5-Fluorouracil in two Intestine Cell Lines
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    Chapter 19 Toxicity and Antitumor Effect of 5-Fluorouracil and its Rescue by Uridine
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    Chapter 20 Synergy of Methotrexate and 6-Mercaptopurine on Cell Growth and Clono- Genicity of Cultured Human T-Lymphoblasts
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    Chapter 21 Increased Availability of Phosphoribosyl Pyrophosphate as the Basis for Enhanced 6-Mercaptopurine Incorporation by Methotrexate, in Cultured Human Lymphoblasts
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    Chapter 22 Regulation of Deoxyadenosine and Nucleoside Analog Phosphorylation by Human Placental Adenosine Kinase
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    Chapter 23 The Biosynthesis of Deoxyguanosine Triphosphate in Herpes Simplex Type-1 Infected Vero Cells Treated with Acyclovir and Hydroxyurea
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    Chapter 24 5-AZA-2′-Deoxycytidine Synergistic action with Thymidine on Leukemic Cells and Interaction of 5-AZA-dCMP with dCMP Deaminase
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    Chapter 25 Selection of Purine Nucleoside Analogs based on Multiple Biological and Biochemical Parameters
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    Chapter 26 Effect of m-AMSA on the cellular pharmacology of ara-CTP in human leukemic cells during therapy with high-dose ara-C.
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    Chapter 27 5-Fluoro-5′-Deoxyuridine is an Inhibitor of Uridylate Nucleotidase in L1210 Leukemaemia
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    Chapter 28 The Effect of Phosphonoformic acid on Wild type and Mutant S49 Cell Lines
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    Chapter 29 Mechanisms of Deoxyguanosine Toxicity for Human T and B Lymphocytes
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    Chapter 30 Role of Intracellular Deoxynucleoside Triphosphate Levels in DNA Repair in Human Lymphocytes
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    Chapter 31 Genetic Analysis of Deoxyadenosine Toxicity in Dividing Human Lymphoblasts
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    Chapter 32 Inhibition of 3 H-Thymidine Incorporation by Adenosine and Deoxyadenosine in Human Peripheral Lymphocytes and Malignant Lymphoid Cell Lines
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    Chapter 33 S-Adenosylmethionine Metabolism as a Target for Adenosine Toxicity
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    Chapter 34 Ethanol Induced Nucleotide Catabolism in Mouse T Lymphoblastoid Cells in Vitro
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    Chapter 35 Increased level of ribonucleotide reductase in deoxyadenosine resistant adenosine deaminase deficient human histiocytic lymphoma cells.
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    Chapter 36 Inhibition of T Cell Cytotoxicity by Cyclosporine (CSA), Adenosine (ADO) and an Inhibitor of Adenosine Deaminase (ADA)
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    Chapter 37 Mechanism of Urate Production by Guinea-Pig Ileum
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    Chapter 38 In Vitro Degradation of Pyrimidine Bases: Studies of Rat Liver Dihydropyrimidine Dehydrogenase
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    Chapter 39 Regulation of Enzymes by Ligand Induced Change in Polymerization
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    Chapter 40 Synthesis and Turnover of Purine Nucleoside Phosphorylase in Human Lymphocytes
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    Chapter 41 Reversible Interconversion Between Sulfo and Desulfo Xanthine Dehydrogenase
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    Chapter 42 Mammalian mutants genetically altered in CTP synthetase activity.
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    Chapter 43 Increased Inosinate Dehydrogenase Activity in Mycophenolic acid Resistant Neuroblastoma Cells
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    Chapter 44 Murine Lymphocytes and Lymphocyte Cell Lines Secrete Adenosine Deaminase
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    Chapter 45 Identification of a Purine 5′-Nucleotidase in Human Erythrocytes
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    Chapter 46 Human Placental Cytoplasmic 5′-Nucleotidase: Kinetics and Molecular Properties
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    Chapter 47 Regulation of the Cytosol 5′-Nucleotidase of the Heart by Adenylate Energy Charge
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    Chapter 48 Characterization of Hydroxyurea (HYU) Resistant S49 T Lymphoma Cells
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    Chapter 49 Purification and Properties of Human Deoxycytidine Kinase
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    Chapter 50 Purification of Mammalian Glycinamide Ribonucleotide (GAR) Synthetase
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    Chapter 51 Steady-State Kinetics of the Reaction Catalyzed by GMP Reductase
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    Chapter 52 Purine De Novo Synthesis and Salvage During Testicular Development in the Rat
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    Chapter 53 Pathways of Adenine Nucleotide Catabolism in Human Erythrocytes
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    Chapter 54 Mechanism of Increased Rate of De Novo Purine Biosynthesis in Rat Liver after Bilateral Adrenalectomy
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    Chapter 55 Increase of Amidophosphoribosyltransferase activity and Phosphoribosylpyrophosphate Concentration as the Basis for increased De Novo Purine Biosynthesis in the Regenerating Rat Liver
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    Chapter 56 Purine Metabolism in Human Neuroblastoma Cell Lines
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    Chapter 57 Purine Biosynthesis in Chinese Hamster Cell Mutants and Human Fibroblasts Partially Deficient in Adenylosuccinate Lyase
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    Chapter 58 Purine Synthetic Capacities of De Novo and Salvage Pathways in Rat Hepatoma 3924A Cells
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    Chapter 59 Metabolism of Purine Nucleotide in the Liver and Kidney of Castrated Rats
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    Chapter 60 The Hormonal Regulation of Purine Biosynthesis: Control of the Inosinic acid Branch Point
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    Chapter 61 Production and Properties of Monoclonal Antibodies against Human Ecto-5′-Nucleotidase
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    Chapter 62 AMP-Deaminase and Cytosolic 5′Nucleotidase in Human and Murine Lymphocyte Subpopulations
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    Chapter 63 An Explanation for the Heterogeneity in B Lymphocyte Ecto-5′-Nucleotidase Activity in Patients with Hypogammaglobulinemia
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    Chapter 64 Cell Surface Adenosine Deaminase (ADA) and its Complexing Protein (ADCP) in Human T-Lymphoid Cells
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    Chapter 65 On the Role of Cytidine Deaminase in Cellular Metabolism
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    Chapter 66 Purine Enzyme Activities as Markers of Lymphocytic Differentiation: Studies of Lymphocytes from Horses with Severe Combined Immunodeficiency (SCID)
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    Chapter 67 The Effects of PNP Inhibition on Rat Lymphoid Cell Populations
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    Chapter 68 Imbalance in nucleotide pools of myeloid leukemia cells and HL-60 cells: correlation with cell cycle phase, cell proliferation and differentiation.
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    Chapter 69 Enhancement of T Cell Proliferation and Differentiation by 8-Mercaptoguanosine
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    Chapter 70 Antigen-Specific Enhancement of the Human Antibody Response by a Substituted Nucleoside
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    Chapter 71 Ectoenzymes of Nucleotide Metabolism on Human Lymphoid Cells
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    Chapter 72 Separate Mechanisms for Cellular uptake of Purine Nucleotides by B- and T-Lymphoblasts
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    Chapter 73 Ecto-5′-Nucleotidase Can use IMP to Provide the Total Purine Requirements of Mitogen-Stimulated Human T Cells and Human B Lymphoblasts
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    Chapter 74 Changes of Purine Metabolism During Differentiation of Rat Heart Myoblasts
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    Chapter 75 Production and Degradation of AMP in Cultured Rat Skeletal and Heart Muscle: A Comparative Study
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    Chapter 76 Duchenne Muscular Dystrophy: Normal ATP Turnover in Cultured Cells
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    Chapter 77 Inferences on the Rapid Metabolism of Exogenously applied ATP in isolated Smooth Muscle Preparations using Pharmacological Studies
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    Chapter 78 Enzyme Activities of Purine Catabolism and Salvage in Human Muscle Tissue
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    Chapter 79 Purine Salvage in Rat Heart Myoblasts
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    Chapter 80 Skeletal Muscle Adenosine, Inosine and Hypoxanthine Release Following Ischaemic Forearm Exercise in Myoadenylate Deaminase Deficiency and McArdle’s Disease
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    Chapter 81 Myoadenylate Deaminase Deficiency: Diagnosis by Forearm Ischemic Exercise Testing
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    Chapter 82 Purine Nucleotides in Human Hearts During Open Heart Surgery
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    Chapter 83 Cell Culture Models for the Study of Purine Metabolism in Human Placental Tissue
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    Chapter 84 Purine Nucleotide Synthesis in Cultured Rat Embryos Undergoing Organogenesis
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    Chapter 85 Evidence for a Membrane Adenosine Receptor in Leishmania Mexicana Mexicana (WR 227)
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    Chapter 86 Adenine Phosphoribosyltransferase-Deficient Leishmania Donovani
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    Chapter 87 5′-Methylthioadenosine (MTA) Phosphorylase from Promastigotes of Leishmania Donovani
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    Chapter 88 6-Thiopurine Riboside Analogs: Their Toxicity and Metabolism in Leishmania Donovani and Mammalian Cells
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    Chapter 89 Purine Salvage Enzymes in Trichomonas Vaginalis
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    Chapter 90 Biochemical Basis for Deoxyadenosine and 2-Chlorodeoxyadenosine Toxicity to Resting Human Lymphocytes
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    Chapter 91 2-Chloroadenosine is Phosphorylated and Increases the Production of Hypoxanthine in Human Cells
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    Chapter 92 Mechanism of Cytotoxicity of 2-Chloro and 2-Bromodeoxyadenosine for a Human Lymphoblastic Cell Line, CCRF-CEM
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    Chapter 93 Genetic and biochemical characteristics of three different types of mutants of mammalian cells affected in adenosine kinase.
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    Chapter 94 Characterization of arabinosylguanine resistance in a lymphoblastoid cell line.
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    Chapter 95 The Synthesis of Phosphoribosylpyrophosphate from Glucose Decreases During Amino Acid Starvation of Human Lymphoblasts
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    Chapter 96 Effect of Fructose on the Concentration of Phosphoribosylpyrophosphate in isolated Hepatocytes
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    Chapter 97 The Mechanism of Insulin-Induced Increase of the Rate of De Novo Purine Biosynthesis in Primary Cultured Rat Hepatocytes
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    Chapter 98 Hormone-Induced Stimulation of Phosphoribosylpyrophosphate and of Purine Synthesis in Mouse Liver in Vivo
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     Chapter 99 Cobalamin Inactivation Decreases Purine and Methionine Synthesis in Cultured Human Lymphoblasts
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     Chapter 100 5′-Deoxy-5′-Methylthioadenosine Phosphorylase Deficiency in Leukemia: Genetics and Biochemical Aspects
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     Chapter 101 Metabolism of 5′-Methylthioadenosine in Methionine-Dependent and Methionine-Independent Cells
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     Chapter 102 Inhibition of De Novo Purine Synthesis by Methylthioadenosine
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     Chapter 103 Determination of S-Adenosylhomocysteine in Tissues Following Pharmacological Inhibition of S-Adenosylhomocysteine Catabolism
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     Chapter 104 4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
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     Chapter 105 In Vivo Inhibition of Mouse Liver Methyltransferase Enzymes Following Treatment with 2′-Deoxycoformycin and 2′-Deoxyadenosine
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     Chapter 106 Alteration of Ribonucleotide and Deoxyribonucleotide Metabolism by Interferon in Human B- Lymphoblastoid Cells
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     Chapter 107 Inhibitor of 2′ 5′-Oligoadenylate Synthetase Induced in Human T Lymphoblastoid Cell Line treated with Deoxyadenosine, Deoxycoformycin and Interferon
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     Chapter 108 2-5A synthetase activities in herpes virus infection and after interferon treatment.