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Thymic Development and Selection of T Lymphocytes

Overview of attention for book
Attention for Chapter 324: Trafficking to the Thymus
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Chapter title
Trafficking to the Thymus
Chapter number 324
Book title
Thymic Development and Selection of T Lymphocytes
Published in
Current topics in microbiology and immunology, April 2013
DOI 10.1007/82_2013_324
Pubmed ID
Book ISBNs
978-3-64-240251-7, 978-3-64-240252-4
Authors

Shirley L. Zhang, Avinash Bhandoola

Abstract

The continuous production of T lymphocytes requires that hematopoietic progenitors developing in the bone marrow migrate to the thymus. Rare progenitors egress from the bone marrow into the circulation, then traffic via the blood to the thymus. It is now evident that thymic settling is tightly regulated by selectin ligands, chemokine receptors, and integrins, among other factors. Identification of these signals has enabled progress in identifying specific populations of hematopoietic progenitors that can settle the thymus. Understanding the nature of progenitor cells and the molecular mechanisms involved in thymic settling may allow for therapeutic manipulation of this process, and improve regeneration of the T lineage in patients with impaired T cell numbers.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 7%
Unknown 13 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 21%
Student > Master 3 21%
Student > Bachelor 2 14%
Professor > Associate Professor 2 14%
Student > Doctoral Student 1 7%
Other 1 7%
Unknown 2 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 36%
Biochemistry, Genetics and Molecular Biology 2 14%
Nursing and Health Professions 1 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 7%
Immunology and Microbiology 1 7%
Other 1 7%
Unknown 3 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2014.
All research outputs
#18,374,472
of 22,758,248 outputs
Outputs from Current topics in microbiology and immunology
#524
of 671 outputs
Outputs of similar age
#146,157
of 194,129 outputs
Outputs of similar age from Current topics in microbiology and immunology
#6
of 8 outputs
Altmetric has tracked 22,758,248 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 671 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 194,129 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.