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Notch Signaling in Embryology and Cancer

Overview of attention for book
Cover of 'Notch Signaling in Embryology and Cancer'

Table of Contents

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    Book Overview
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    Chapter 1 The Molecular Basis of Notch Signaling: A Brief Overview
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    Chapter 2 The Role of Adams in Notch Signaling
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    Chapter 3 Metabolism and Transportation Pathways Of GDP-Fucose that are Required for the O -Fucosylation Of Notch
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    Chapter 4 Notch Signaling and the Generation of Cell Diversity in Drosophila Neuroblast Lineages
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    Chapter 5 NEPRO: A Novel Notch Effector for Maintenance of Neural Progenitor Cells in the Neocortex
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    Chapter 6 Notch Signaling and Development of the Hematopoietic System
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    Chapter 7 Notch signaling in lung development and disease.
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    Chapter 8 The Role of Notch Signaling in Kidney Development and Disease
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    Chapter 9 Notch Signaling and the Developing Skeleton
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    Chapter 10 Notch signaling and the developing skin epidermis.
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    Chapter 11 Notch Signaling and the Developing Hair Follicle
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    Chapter 12 Notch Signaling and the Developing Inner Ear
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    Chapter 13 Notch signaling in cancer stem cells.
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    Chapter 14 Notch Signaling Pathway and Cancer Metastasis
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    Chapter 15 Notch, Apoptosis and Cancer
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    Chapter 16 Ligand-dependent notch signaling in vascular formation.
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    Chapter 17 Notch and the p53 Clan of Transcription Factors
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    Chapter 18 Notch signaling and breast cancer.
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    Chapter 19 Notch Signaling and Malignant Melanoma
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    Chapter 20 Notch-Signaling and Nonmelanoma Skin Cancer: An Ancient Friend, Revisited
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    Chapter 21 Notch Signaling and Intestinal Cancer
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    Chapter 22 Notch Signaling and Brain Tumors
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    Chapter 23 NOTCH INHIBITION AS A PROMISING NEW APPROACH TO CANCER THERAPY
Attention for Chapter 7: Notch signaling in lung development and disease.
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Chapter title
Notch signaling in lung development and disease.
Chapter number 7
Book title
Notch Signaling in Embryology and Cancer
Published in
Advances in experimental medicine and biology, March 2012
DOI 10.1007/978-1-4614-0899-4_7
Pubmed ID
Book ISBNs
978-1-4614-0898-7, 978-1-4614-0899-4
Authors

Xu K, Moghal N, Egan SE, Keli Xu, Nadeem Moghal, Sean E. Egan

Abstract

Notch signaling plays an essential role in development and homeostasis of multiple organs including the lung. Dysregulation of Notch signaling has been implicated in various lung diseases including lung cancer. Here we review functions of Notch signaling in coordinating events during lung development, such as early proximodistal fate generation and branching, airway epithelial cell fate specification, alveogenesis and pulmonary vascular development. We also discuss roles of Notch in chronic obstructive pulmonary disease, progressive pulmonary fibrosis, pulmonary arterial hypertension, asthma and lung cancer.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 1%
Sweden 1 1%
Unknown 79 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 25%
Researcher 14 17%
Student > Bachelor 10 12%
Student > Master 9 11%
Student > Postgraduate 7 9%
Other 13 16%
Unknown 8 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 25%
Biochemistry, Genetics and Molecular Biology 18 22%
Medicine and Dentistry 18 22%
Engineering 4 5%
Immunology and Microbiology 2 2%
Other 8 10%
Unknown 11 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2012.
All research outputs
#20,156,199
of 22,664,267 outputs
Outputs from Advances in experimental medicine and biology
#3,932
of 4,903 outputs
Outputs of similar age
#141,754
of 156,530 outputs
Outputs of similar age from Advances in experimental medicine and biology
#23
of 27 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,903 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,530 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.