Chapter 1 Progress and Trends in Complement Therapeutics

Chapter 2 Inhibition of the Serine Proteases of the Complement System

Chapter 3 The Role of MASP-1/3 in Complement Activation

Chapter 5 DAF as a Therapeutic Target for Steroid Hormones: Implications for Host–Pathogen Interactions

Chapter 6 Targeting gC1qR Domains for Therapy Against Infection and Inflammation.

Chapter 7 The Alternative C5a Receptor Function

Chapter 8 The Effects of Selective Complement and CD14 Inhibition on the E. coli -Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood

Chapter 9 CR2-Mediated Targeting of Complement Inhibitors: Bench-to-Bedside Using a Novel Strategy for Site-Specific Complement Modulation

Chapter 10 Paroxysmal Nocturnal Hemoglobinuria and the Complement System: Recent Insights and Novel Anticomplement Strategies

Chapter 11 Defective Complement Action and Control Defines Disease Pathology for Retinal and Renal Disorders and Provides a Basis for New Therapeutic Approaches

Chapter 12 C3 Glomerulonephritis/CFHR5 Nephropathy Is an Endemic Disease in Cyprus: Clinical and Molecular Findings in 21 Families

Chapter 13 Complement-Targeted Therapeutics in Periodontitis

Chapter 14 Complement System Activation in Cardiac and Skeletal Muscle Pathology: Friend or Foe?

Chapter 15 Innate Immunity as Orchestrator of Bone Marrow Homing for Hematopoietic Stem/Progenitor Cells

Chapter 16 Complement-Mediated Microvascular Injury Leads to Chronic Rejection

Chapter 17 Targeting Complement at the Time of Transplantation

Chapter 18 Evaluation of the Blood Compatibility of Materials, Cells, and Tissues: Basic Concepts, Test Models, and Practical Guidelines

Chapter 19 Noninvasive Detection of Complement Activation Through Radiologic Imaging

Chapter 20 Complement Therapeutics

Chapter 21 Complement in Action: An Analysis of Patent Trends from 1976 Through 2011