Chapter 1 Design and Implementation of High-Throughput Screening Assays

Chapter 2 Creation of a Small High-Throughput Screening Facility

Chapter 3 Informatics in Compound Library Management

Chapter 4 Statistics and Decision Making in High-Throughput Screening

Chapter 6 Application of Fluorescence Polarization in HTS Assays

Chapter 7 Screening G Protein-Coupled Receptors: Measurement of Intracellular Calcium Using the Fluorometric Imaging Plate Reader

Chapter 8 High-Throughput Automated Confocal Microscopy Imaging Screen of a Kinase-Focused Library to Identify p38 Mitogen-Activated Protein Kinase Inhibitors Using the GE InCell 3000 Analyzer

Chapter 9 Recent Advances in Electrophysiology-Based Screening Technology and the Impact upon Ion Channel Discovery Research

Chapter 10 Automated patch clamping using the QPatch.

Chapter 11 High-Throughput Screening of the Cyclic AMP-Dependent Protein Kinase (PKA) Using the Caliper Microfluidic Platform

Chapter 12 Use of Primary Human Cells in High-Throughput Screens