| Chapter title |
Hematopoietic Stem Cell Mobilization with Agents Other than G-CSF.
|
|---|---|
| Chapter number | 4 |
| Book title |
Stem Cell Mobilization
|
| Published in |
Methods in molecular biology, January 2012
|
| DOI | 10.1007/978-1-61779-943-3_4 |
| Pubmed ID | |
| Book ISBNs |
978-1-61779-942-6, 978-1-61779-943-3
|
| Authors |
Hoggatt J, Pelus LM, Jonathan Hoggatt, Louis M. Pelus, Hoggatt, Jonathan, Pelus, Louis M. |
| Abstract |
Hematopoietic stem and progenitor mobilization has revolutionized the field of hematopoietic transplantation. Currently, hematopoietic grafts acquired from the peripheral blood of patients or donors treated with granulocyte-colony stimulating factor (G-CSF) are the preferred source for transplantation. G-CSF mobilization regimens, however, are associated with known morbidities and a significant number of normal donors and patient populations fail to mobilize sufficient numbers of hematopoietic stem and progenitor cells for transplantation, necessitating the need for non-G-CSF mobilization strategies. Mechanistic studies evaluating hematopoietic bone marrow niche interactions have uncovered novel agents with the capacity for hematopoietic mobilization. This chapter provides a comprehensive overview of mobilizing agents, other than G-CSF, and experimental procedures and technical aspects important to evaluate and define their hematopoietic mobilizing activities alone and in combination. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 15 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor > Associate Professor | 2 | 13% |
| Student > Ph. D. Student | 2 | 13% |
| Student > Doctoral Student | 1 | 7% |
| Student > Bachelor | 1 | 7% |
| Professor | 1 | 7% |
| Other | 2 | 13% |
| Unknown | 6 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 27% |
| Immunology and Microbiology | 1 | 7% |
| Veterinary Science and Veterinary Medicine | 1 | 7% |
| Sports and Recreations | 1 | 7% |
| Chemistry | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 7 | 47% |