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Human Antibody Therapeutics for Viral Disease

Overview of attention for book
Attention for Chapter 6: Exploring the native human antibody repertoire to create antiviral therapeutics.
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

patent
1 patent
wikipedia
1 Wikipedia page

Citations

dimensions_citation
2 Dimensions

Readers on

mendeley
21 Mendeley
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Chapter title
Exploring the native human antibody repertoire to create antiviral therapeutics.
Chapter number 6
Book title
Human Antibody Therapeutics for Viral Disease
Published in
Current topics in microbiology and immunology, January 2008
DOI 10.1007/978-3-540-72146-8_6
Pubmed ID
Book ISBNs
978-3-54-072144-4, 978-3-54-072146-8
Authors

S K Dessain, S P Adekar, J D Berry, Dessain, Scott K., Adekar, S. P., Berry, J. D., Scott K. Dessain, S. P. Adekar, J. D. Berry

Abstract

Native human antibodies are defined as those that arise naturally as the result of the functioning of an intact human immune system. The utility of native antibodies for the treatment of human viral diseases has been established through experience with hyperimmune human globulins. Native antibodies, as a class, differ in some respects from those obtained by recombinant library methods (phage or transgenic mouse) and possess distinct properties that may make them ideal therapeutics for human viral diseases. Methods for cloning native human antibodies have been beset by technical problems, yet many antibodies specific for viral antigens have been cloned. In the present review, we discuss native human antibodies and ongoing improvements in cloning methods that should facilitate the creation of novel, potent antiviral therapeutics obtained from the native human antibody repertoire.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 33%
Other 3 14%
Student > Master 3 14%
Student > Doctoral Student 1 5%
Lecturer > Senior Lecturer 1 5%
Other 1 5%
Unknown 5 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 33%
Medicine and Dentistry 3 14%
Biochemistry, Genetics and Molecular Biology 2 10%
Engineering 2 10%
Immunology and Microbiology 1 5%
Other 0 0%
Unknown 6 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2018.
All research outputs
#4,696,673
of 22,789,076 outputs
Outputs from Current topics in microbiology and immunology
#118
of 672 outputs
Outputs of similar age
#22,121
of 156,211 outputs
Outputs of similar age from Current topics in microbiology and immunology
#2
of 17 outputs
Altmetric has tracked 22,789,076 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 672 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 156,211 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.