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Attention Score in Context
| Chapter title |
Immunoaffinity purification and quantification of antibody-toxin conjugates.
|
|---|---|
| Chapter number | -896031748 |
| Book title |
Immunochemical Protocols
|
| Published in |
Methods in molecular biology, January 1992
|
| DOI | 10.1385/0-89603-204-3:295 |
| Pubmed ID | |
| Book ISBNs |
978-0-89603-204-0, 978-1-59259-497-9
|
| Authors |
Wawrzynczak, E J, Cumber, A J, Edward J. Wawrzynczak, Alan J. Cumber |
| Abstract |
Cytotoxic antibody-toxin conjugates made using antibodies and ribs some-inactivating proteins (RIPs) are prepared using chemical crosslinking methods (1,2 and this vol., Chapter 31 ). Gel permeation chromatography is used as a first step to purify conjugate molecules from the reaction mixture. This procedure removes protein aggregates, the excess of RIP employed in the conjugation reaction, and low molecular weight byproducts. However, a significant fraction of the resulting conjugate preparation consists of unconjugated antibody that cannot be completely separated from the conjugate on the basis of size discrimination alone (see chapter 31 ). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2012.
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#18,320,524
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Outputs from Methods in molecular biology
#7,833
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#59,751
of 61,494 outputs
Outputs of similar age from Methods in molecular biology
#1
of 1 outputs
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