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Retinal Degenerative Diseases

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Cover of 'Retinal Degenerative Diseases'

Table of Contents

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    Book Overview
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    Chapter 1 A Window to Innate Neuroimmunity: Toll-Like Receptor-Mediated Cell Responses in the Retina
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    Chapter 2 Retinal Degenerative Diseases
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    Chapter 3 Local Vs. Systemic Mononuclear Phagocytes in Age-Related Macular Degeneration and Their Regulation by CCL2–CCR2 and CX3CL1–CX3CR1 Chemokine Signalling
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    Chapter 4 Sublytic membrane-attack-complex activation and VEGF secretion in retinal pigment epithelial cells.
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    Chapter 5 Retinal Degenerative Diseases
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    Chapter 6 Microglia in the Outer Retina and Their Relevance to Pathogenesis of Age-Related Macular Degeneration
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    Chapter 7 Lutein or Zeaxanthin Supplementation Suppresses Inflammatory Responses in Retinal Pigment Epithelial Cells and Macrophages
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    Chapter 8 Exploring the Potential Role of the Oxidant-Activated Transcription Factor Aryl Hydrocarbon Receptor in the Pathogenesis of AMD.
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    Chapter 9 Common Mechanisms for Separate Maculopathies?
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    Chapter 10 The Role of Amyloid-β in Retinal Degeneration
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    Chapter 11 Molecule-Specific Imaging and Quantitation of A2E in the RPE
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    Chapter 12 Autophagy in the Retina: A Potential Role in Age-Related Macular Degeneration
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    Chapter 13 Regeneration of Cone Outer Segments Induced by CNTF
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    Chapter 14 Glucocorticoid-Dependent Mechanisms in Photoreceptor Survival
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    Chapter 15 HDAC Inhibition Prevents Rd1 Mouse Photoreceptor Degeneration
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    Chapter 16 Neuroprotective Dose Response in RCS Rats Implanted with Microphotodiode Arrays
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    Chapter 17 Treatment with 670-nm Light Protects the Cone Photoreceptors from White Light-Induced Degeneration
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    Chapter 18 Dark-Rearing the rd10 Mouse: Implications for Therapy
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    Chapter 19 Intravitreal Injection of Erythropoietin Glycosylation Analogs Does Not Protect Rod Photoreceptor Cells from Light-Induced Damage
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    Chapter 20 Relieving Bottlenecks in RNA Drug Discovery for Retinal Diseases
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    Chapter 21 On Further Development of Barrier Modulation as a Technique for Systemic Ocular Drug Delivery
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    Chapter 22 An Application for Mammalian Optic Nerve Repair by Fish Regeneration-Associated Genes
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    Chapter 23 The Mechanism of Fenretinide (4-HPR) Inhibition of β-carotene Monooxygenase 1. New Suspect for the Visual Side Effects of Fenretinide
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    Chapter 24 Gene Augmentation Trials Using the Rpe65-Deficient Dog: Contributions Towards Development and Refinement of Human Clinical Trials
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    Chapter 25 Gene Therapy Restores Missing Cone-Mediated Vision in the CNGA3 −/− Mouse Model of Achromatopsia
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    Chapter 26 Functional Rescue of P23H Rhodopsin Photoreceptors by Gene Delivery
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    Chapter 27 Gene Delivery of Wild-Type Rhodopsin Rescues Retinal Function in an Autosomal Dominant Retinitis Pigmentosa Mouse Model
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    Chapter 28 Retinal Degeneration and Cellular Suicide
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    Chapter 29 Suppression of rds Expression by siRNA and Gene Replacement Strategies for Gene Therapy Using rAAV Vector
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    Chapter 30 Silencing the Expression of CTRP5 / C1QTNF5 and ELOVL4 Genes by Small Interfering RNA
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    Chapter 31 Gene Therapy Strategies for Usher Syndrome Type 1B
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    Chapter 32 Neovascularization: Ocular Diseases, Animal Models and Therapies
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    Chapter 33 Retinal Neovascular Disorders: Mouse Models for Drug Development Studies
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    Chapter 34 A Review and Update on the Molecular Basis of Pathogenesis of Sorsby Fundus Dystrophy
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    Chapter 35 The Importance of Hypoxia-Regulated, RPE-Targeted Gene Therapy for Choroidal Neovascularization
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    Chapter 36 What Is the Role of CCR3 in Choroidal Neovascularization?
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    Chapter 37 Intermittent But Not Constant High Glucose Induces ER Stress and Inflammation in Human Retinal Pericytes
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    Chapter 38 Regulation of Retinal Vascular Permeability by Betacellulin
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    Chapter 39 Presence of RPE-Produced VEGF in a Timely Manner Is Critical to Choroidal Vascular Development.
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    Chapter 40 Vasohibin-1 and retinal pigment epithelium.
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    Chapter 41 Polymorphic Variation of RPGRIP1L and IQCB1 as Modifiers of X-Linked Retinitis Pigmentosa Caused by Mutations in RPGR
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    Chapter 42 RPGRIP1 and Cone-Rod Dystrophy in Dogs.
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    Chapter 43 High-Throughput Approaches for the Genetic Diagnosis of Retinal Dystrophies
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    Chapter 44 Genes and Mutations in Autosomal Dominant Cone and Cone-Rod Dystrophy
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    Chapter 45 The Power of Homozygosity Mapping: Discovery of New Genetic Defects in Patients with Retinal Dystrophy
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    Chapter 46 Development and Validation of a Canine-Specific Profiling Array to Examine Expression of Pro-apoptotic and Pro-survival Genes in Retinal Degenerative Diseases
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    Chapter 47 The chromosome 10q26 susceptibility locus in age-related macular degeneration.
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    Chapter 48 Congenital Stationary Night Blindness: Mutation Update and Clinical Variability
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    Chapter 49 Serum biomarkers and trafficking defects in peripheral tissues reflect the severity of retinopathy in three brothers affected by choroideremia.
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    Chapter 50 Translational Vision Research Models Program
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    Chapter 51 Zebrafish: A Model System for the Investigation of Novel Treatments for Retinal Disease
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    Chapter 52 Retinal Degeneration in the Fly
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    Chapter 53 Looking into Eyes: Rhodopsin Pathologies in Drosophila
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    Chapter 54 Müller Glia as a Source of Neuronal Progenitor Cells to Regenerate the Damaged Zebrafish Retina
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    Chapter 55 Retinal Degenerative Diseases
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    Chapter 56 Factor XIIIA Induction in the Retina and Optic Nerve After Optic Nerve Lesion in Goldfish
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    Chapter 57 Imaging the Photoreceptor Mosaic with Adaptive Optics: Beyond Counting Cones
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    Chapter 58 Baseline Imaging Reveals Preexisting Retinal Abnormalities in Mice
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    Chapter 59 Correlation Between Spectral Domain OCT Retinal Nerve Fibre Layer Thickness and Multifocal Pattern Electroretinogram in Advanced Retinitis Pigmentosa
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    Chapter 60 Imaging Human Postmortem Eyes with SLO and OCT.
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    Chapter 61 In Vivo Assessment of Rodent Retinal Structure Using Spectral Domain Optical Coherence Tomography
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    Chapter 62 Rod Photoreceptor Temporal Properties in Retinal Degenerative Diseases
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    Chapter 63 ERG Critical Flicker Frequency Assessment in Humans
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    Chapter 64 Biology of Retinoschisin
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    Chapter 65 Transcriptome Analyses to Investigate the Pathogenesis of RNA Splicing Factor Retinitis Pigmentosa
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    Chapter 66 The Role of the X-linked Retinitis Pigmentosa Protein RP2 in Vesicle Traffic and Cilia Function
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    Chapter 67 Caenorhabditis elegans as a Model Organism for Ciliopathies and Related Forms of Photoreceptor Degeneration
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    Chapter 68 Towards a Pathological Mechanism for IMPDH1-Linked Retinitis Pigmentosa
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    Chapter 69 Calpain and Photoreceptor Apoptosis
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    Chapter 70 Ceramide Signaling in Retinal Degeneration
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    Chapter 71 Endoplasmic Reticulum-Associated Degradation (ERAD) of Misfolded Glycoproteins and Mutant P23H Rhodopsin in Photoreceptor Cells
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    Chapter 72 Protein Misfolding and Potential Therapeutic Treatments in Inherited Retinopathies
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    Chapter 73 Development of a cellular model of rod opsin retinitis pigmentosa.
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    Chapter 74 A Brief Account of Rho GTPases in Retinal Physiology and Pathophysiology
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    Chapter 75 Molecular Clues to Bothnia-Type Retinal Dystrophy
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    Chapter 76 A Novel Missense Mutation in Both OPN1LW and OPN1MW Cone Opsin Genes Causes X-Linked Cone Dystrophy (XLCOD5)
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    Chapter 77 A Potential Cytosolic Function of Bestrophin-1
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    Chapter 78 Modeling the Structural Consequences of BEST1 Missense Mutations.
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    Chapter 79 Microglial Activation and Transcriptomic Changes in the Blue Light-Exposed Mouse Retina
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    Chapter 80 Overexpression of ROM-1 in the Cone-Dominant Retina
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    Chapter 81 Analysis of the RPE Sheet in the rd10 Retinal Degeneration Model
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    Chapter 82 Networks Modulating the Retinal Response to Injury: Insights from Microarrays, Expression Genetics, and Bioinformatics
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    Chapter 83 Mislocalization of Oligomerization-Incompetent RDS is Associated with Mislocalization of Cone Opsins and Cone Transducin
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    Chapter 84 HSP70 Gene Expression in the Zebrafish Retina After Optic Nerve Injury: A Comparative Study Under Heat Shock Stresses
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    Chapter 85 Restoration of retinal development in vsx2 deficient mice by reduction of gdf11 levels.
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    Chapter 86 The Different Functions of Norrin
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    Chapter 87 Roles of Homeobox Genes in Retinal Ganglion Cell Differentiation and Axonal Guidance
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    Chapter 88 Unraveling the Molecular Mystery of Retinal Pigment Epithelium Phagocytosis
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    Chapter 89 Isolating Photoreceptor Compartment-Specific Protein Complexes for Subsequent Proteomic Analysis
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    Chapter 90 Expression of the Integrin Coreceptor Transglutaminase-2 in the RPE In Vivo and in Culture
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    Chapter 91 On Your Marks… Get Bound… Internalize!
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    Chapter 92 Endo-Lysosome Function in the Retinal Pigment Epithelium in Health and Disease
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    Chapter 93 αvβ5 Integrin-Dependent Diurnal Phagocytosis of Shed Photoreceptor Outer Segments by RPE Cells Is Independent of the Integrin Coreceptor Transglutaminase-2
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    Chapter 94 Trafficking of Presynaptic PMCA Signaling Complexes in Mouse Photoreceptors Requires Cav1.4 α 1 Subunits
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    Chapter 95 Roles for AMP-Activated Protein Kinase in RPE Cell Function
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    Chapter 96 Genome-Wide Occupancy Analysis by ChIP-chip and ChIP-Seq
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    Chapter 97 The Bisretinoids of RPE Lipofuscin: A Complex Mixture
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    Chapter 98 Biochemical Characterization of Cone Cyclic Nucleotide-Gated (CNG) Channel Using the Infrared Fluorescence Detection System
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    Chapter 99 Ras-associating domain proteins: a new class of cyclic nucleotide-gated channel modulators.
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    Chapter 100 Tulp1 Is Involved in Specific Photoreceptor Protein Transport Pathways
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    Chapter 101 Potential Cellular Functions of N -Ethylmaleimide Sensitive Factor in the Photoreceptor
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    Chapter 102 Identification of Pigment Epithelium-Derived Factor Receptor (PEDF-R) Antibody Epitopes
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    Chapter 103 HCN1 Channels Significantly Shape Retinal Photoresponses
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    Chapter 104 Retinal Degenerative Diseases
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    Chapter 105 A Tale of Two Kinases in Rods and Cones
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    Chapter 106 Protein Tyrosine Phosphatase 1B: A Novel Molecular Target for Retinal Degenerative Diseases.
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    Chapter 107 Protein Tyrosine- O -Sulfation in Bovine Ocular Tissues
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    Chapter 108 Erratum to: HCN1 Channels Significantly Shape Retinal Photoresponses
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Title
Retinal Degenerative Diseases
Published by
Springer, Boston, MA, December 2011
DOI 10.1007/978-1-4614-0631-0
ISBNs
978-1-4614-0630-3, 978-1-4614-0631-0
Editors

Matthew M. LaVail, John D. Ash, Robert E. Anderson, Joe G. Hollyfield, Christian Grimm

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 39%
Student > Ph. D. Student 4 22%
Professor 2 11%
Student > Doctoral Student 1 6%
Other 1 6%
Other 1 6%
Unknown 2 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 44%
Neuroscience 3 17%
Immunology and Microbiology 2 11%
Arts and Humanities 1 6%
Medicine and Dentistry 1 6%
Other 1 6%
Unknown 2 11%