Chapter 1 Historical Development of Monoclonal Antibody Therapeutics

Chapter 2 Preclinical Safety Evaluation of Monoclonal Antibodies

Chapter 3 Engineering Antibodies for Stability and Efficient Folding

Chapter 4 Human Monoclonal Antibodies from Transgenic Mice

Chapter 5 Anti-TNF Antibodies: Lessons from the Past, Roadmap for the Future

Chapter 6 Therapeutic Anti-VEGF Antibodies

Chapter 7 Humanized Antihuman IL-6 Receptor Antibody, Tocilizumab

Chapter 8 Anti-CD20Monoclonal Antibody in Rheumatoid Arthritis and Systemic Lupus Erythematosus

Chapter 9 Herceptin

Chapter 10 The Use of CD3-Specific Antibodies in Autoimmune Diabetes: A Step Toward the Induction of Immune Tolerance in the Clinic

Chapter 11 Monoclonal Antibody Therapy for Prostate Cancer

Chapter 13 Cytokine, Chemokine, and Co-Stimulatory Fusion Proteins for the Immunotherapy of Solid Tumors

Chapter 14 The T-Body Approach: Redirecting T Cells with Antibody Specificity

Chapter 15 Intracellular Antibodies (Intrabodies) and Their Therapeutic Potential