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Chromothripsis

Overview of attention for book
Cover of 'Chromothripsis'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 The Genomic Characteristics and Origin of Chromothripsis
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    Chapter 2 Clinical Consequences of Chromothripsis and Other Catastrophic Cellular Events
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    Chapter 3 Potential Role of Chromothripsis in the Genesis of Complex Chromosomal Rearrangements in Human Gametes and Preimplantation Embryo
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    Chapter 4 Chromothripsis and the Macroevolution Theory
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    Chapter 5 Analysis of Chromothripsis by Combined FISH and Microarray Analysis
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    Chapter 6 Chromothripsis Detectable in Small Supernumerary Marker Chromosomes (sSMC) Using Fluorescence In Situ Hybridization (FISH)
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    Chapter 7 Identification of Chromothripsis in Biopsy Using SNP-Based Microarray
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    Chapter 8 Detection of Chromothripsis in Plants
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    Chapter 9 RNA-Seq Analysis to Detect Abnormal Fusion Transcripts Linked to Chromothripsis
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    Chapter 10 Experimental Determination of Checkpoint Adaptation by Mitotic Shake-Off and Microscopy
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    Chapter 11 A Role for Retrotransposons in Chromothripsis
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    Chapter 12 Generation of Micronuclei and Detection of Chromosome Pulverization
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    Chapter 13 Detection of Impaired DNA Replication and Repair in Micronuclei as Indicators of Genomic Instability and Chromothripsis
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    Chapter 14 Study of Telomere Dysfunction in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability
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    Chapter 15 Genes, Proteins, and Biological Pathways Preventing Chromothripsis
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    Chapter 16 Expression of Genes Associated with Telomere Homeostasis in TP53 Mutant LoVo Cell Lines as a Model for Genomic Instability
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    Chapter 17 Chromothripsis Detection and Characterization Using the CTLPScanner Web Server
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    Chapter 18 ChromothripsisDB: A Curated Database for the Documentation, Visualization, and Mining of Chromothripsis Data
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    Chapter 19 Time-Lapse Imaging for the Detection of Chromosomal Abnormalities in Primate Preimplantation Embryos
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    Chapter 20 Correlative Live Imaging and Immunofluorescence for Analysis of Chromosome Segregation in Mouse Preimplantation Embryos
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    Chapter 21 Experimental Induction of Genome Chaos
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    Chapter 22 Looking for Broken TAD Boundaries and Changes on DNA Interactions: Clinical Guide to 3D Chromatin Change Analysis in Complex Chromosomal Rearrangements and Chromothripsis
Attention for Chapter 22: Looking for Broken TAD Boundaries and Changes on DNA Interactions: Clinical Guide to 3D Chromatin Change Analysis in Complex Chromosomal Rearrangements and Chromothripsis
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  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

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Chapter title
Looking for Broken TAD Boundaries and Changes on DNA Interactions: Clinical Guide to 3D Chromatin Change Analysis in Complex Chromosomal Rearrangements and Chromothripsis
Chapter number 22
Book title
Chromothripsis
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7780-2_22
Pubmed ID
Book ISBNs
978-1-4939-7779-6, 978-1-4939-7780-2
Authors

Kevin Yauy, Vincent Gatinois, Thomas Guignard, Satish Sati, Jacques Puechberty, Jean Baptiste Gaillard, Anouck Schneider, Franck Pellestor

Abstract

Apparition of next-generation sequencing (NGS) was a breakthrough on knowledge of genome structure. Bioinformatic tools are a key point to analyze this huge amount of data from NGS and characterize the three-dimensional organization of chromosomes. This chapter describes usage of different browsers to explore publicly available online data and to search for possible 3D chromatin changes involved during complex chromosomal rearrangements as chromothripsis. Their pathogenic impact on clinical phenotype and gene misexpression can also be evaluated with annotated databases.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 21%
Student > Ph. D. Student 3 21%
Researcher 3 21%
Student > Bachelor 2 14%
Professor > Associate Professor 1 7%
Other 0 0%
Unknown 2 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 64%
Agricultural and Biological Sciences 2 14%
Computer Science 1 7%
Unknown 2 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 April 2018.
All research outputs
#15,445,744
of 23,028,364 outputs
Outputs from Methods in molecular biology
#5,344
of 13,175 outputs
Outputs of similar age
#268,675
of 442,381 outputs
Outputs of similar age from Methods in molecular biology
#592
of 1,499 outputs
Altmetric has tracked 23,028,364 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,175 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,381 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,499 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.