Trisomy 21

Chapter 1 Introduction to the Symposium

Chapter 2 Clinical Aspects of Down’s Syndrome from Infancy to Adult Life

Chapter 3 Down’s Syndrome: Problems of Immunodeficiency

Chapter 5 Pathology of Trisomy 21 — with Particular Reference to Persistent Common Atrioventricular Canal of the Heart

Chapter 6 Down’s Syndrome and the Family

Chapter 7 Asking for a Prenatal Diagnosis After the Birth of a Child with Down’s Syndrome

Chapter 8 Vingt Ans Après

Chapter 9 Nondisjunction

Chapter 10 Experiments on Chiasmata and Nondisjunction in Mice

Chapter 11 Gene Mapping and Chromosome 21: History and Methodology

Chapter 12 Functional Implications of Gene Dosage Effects in Trisomy 21

Chapter 13 Structural Variation of Chromosome 21 and Symptoms of Down’s Syndrome

Chapter 14 Prenatal Losses of Trisomy 21

Chapter 15 Incidence of Down’s Syndrome in Sweden During the Years 1968–1977

Chapter 16 Epidemiology of Trisomy 21: Population, Peri- and Antenatal Data