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Mendeley readers
| Chapter title |
Requirements for Using iPSC-Based Cell Models for Assay Development in Drug Discovery
|
|---|---|
| Chapter number | 23 |
| Book title |
Engineering and Application of Pluripotent Stem Cells
|
| Published in |
Advances in biochemical engineering biotechnology, January 2017
|
| DOI | 10.1007/10_2017_23 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-973590-0, 978-3-31-973591-7
|
| Authors |
Klaus Christensen, Filip Roudnicky, Christoph Patsch, Mark Burcin |
| Abstract |
A prevalent challenge in drug discovery is the translation of findings from preclinical research into clinical success. Currently, more physiological in vitro systems are being developed to overcome some of these challenges. In particular, induced pluripotent stem cells (iPSCs) have provided the opportunity to generate human cell types that can be utilized for developing more disease-relevant cellular assay models. As the use of these complex models is lengthy and fairly complicated, we lay out our experiences of the cultivation, differentiation, and quality control requirements to successfully utilize pluripotent stem cells in drug discovery. |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 3 | 25% |
| Student > Bachelor | 1 | 8% |
| Student > Doctoral Student | 1 | 8% |
| Researcher | 1 | 8% |
| Student > Postgraduate | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 5 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 5 | 42% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 8% |
| Agricultural and Biological Sciences | 1 | 8% |
| Neuroscience | 1 | 8% |
| Unknown | 4 | 33% |