Molecular Toxicology Protocols

Table of Contents

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   Book Overview
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   Chapter -1592598401 <SUP>32</SUP>P-Postlabeling Analysis of DNA Adducts
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   Chapter -1592598391 Modification of the <SUP>32</SUP>P-Postlabeling Method to Detect a Single Adduct Species as a Single Spot
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   Chapter -1592598383 DNA Isolation and Sample Preparation for Quantification of Adduct Levels by Accelerator Mass Spectrometry
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   Chapter -1592598375 Fluoroimaging-Based Immunoassay of DNA Photoproducts in Ultraviolet-B-Irradiated Tadpoles
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   Chapter -1592598365 Analysis of DNA Strand Cleavage at Abasic Sites
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   Chapter -1592598355 Premature Chromosome Condensation in Human Resting Peripheral Blood Lymphocytes for Chromosome Aberration Analysis Using Specific Whole-Chromosome DNA Hybridization Probes
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   Chapter -1592598345 Mutagen-Induced Chromatid Breakage as a Marker of Cancer Risk
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   Chapter -1592598335 Flow Cytometric Analysis of Micronuclei in Erythrocytes
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    Chapter -1592598319 The Comet Assay: A Sensitive Genotoxicity Test for the Detection of DNA Damage
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    Chapter -1592598307 Computerized Image Analysis Software for the Comet Assay
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    Chapter -1592598297 The Comet–FISH Technique: A Tool for Detection of Specific DNA Damage and Repair
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    Chapter -1592598283 DNA Double-Strand Break Damage and Repair Assessed by Pulsed-Field Gel Electrophoresis
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    Chapter -1592598271 Analysis of In Vivo Mutation in the Hprt and Tk Genes of Mouse Lymphocytes
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    Chapter -1592598259 Quantifying In Vivo Somatic Mutations Using Transgenic Mouse Model Systems
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    Chapter -1592598249 Methods for Detecting Somatic Mutations In Vitro: The Human T-Cell Cloning Assay Selecting for <i>HPRT</I> Mutants
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    Chapter -1592598243 Molecular Analysis of Mutations in the Human <I>HPRT</I> Gene
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    Chapter -1592598233 Simultaneous Quantification of t(14;18) and <I>HPRT</I> Exon 2/3 Deletions in Human Lymphocytes
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    Chapter -1592598225 The <I>GPA </I>In Vivo Somatic Mutation Assay
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    Chapter -1592598207 Flow Cytometric Measurement of Mutant T Cells With Altered Expression of <I>TCR</I>: Detecting Somatic Mutations in Humans and Mice
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    Chapter -1592598197 Mutation Screening of the <I>TP53</I> Gene by Temporal Temperature Gradient Gel Electrophoresis
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    Chapter -1592598187 Analysis of K<I>-RAS</I> and <I>P53</I> Mutations in Sputum Samples
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    Chapter -1592598169 Allele-Specific Competitive Blocker–PCR Detection of Rare Base Substitution
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    Chapter -1592598157 Gel-Based Nonradioactive Single-Strand Conformational Polymorphism and Mutation Detection: Limitations and Solutions
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    Chapter -1592598141 Detection and Characterization of Oncogene Mutations in Preneoplastic and Early Neoplastic Lesions
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    Chapter -1592598125 Detection of DNA Double-Strand Breaks and Chromosome Translocations Using Ligation-Mediated PCR and Inverse PCR
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    Chapter -1592598111 Microsatellite Instability: An Indirect Assay to Detect Defects in the Cellular Mismatch Repair Machinery
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    Chapter -1592598101 Unscheduled DNA Synthesis: A Functional Assay for Global Genomic Nucleotide Excision Repair
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    Chapter -1592598083 Molecular Toxicology Protocols
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    Chapter -1592598067 An Immunoassay for Measuring Repair of Ultraviolet Photoproducts
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    Chapter -1592598053 Analysis of DNA Double-Strand Break Repair by Nonhomologous End Joining in Cell-Free Extracts From Mammalian Cells
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    Chapter -1592598031 Measuring Recombination Proficiency in Mouse Embryonic Stem Cells
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    Chapter -1592598017 Strategies for Measurement of Biotransformation Enzyme Gene Expression
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    Chapter -1592598005 Genotyping Technologies: Application to Biotransformation Enzyme Genetic Polymorphism Screening
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    Chapter -1592597989 TaqMan<SUP>® </SUP>Fluorogenic Detection System to Analyze Gene Transcription in Autopsy Material
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    Chapter -1592597981 Development of Quantitative Reverse Transcriptase PCR Assays for Measuring Gene Expression
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    Chapter -1592597955 Quantification of Selective Phosphatidylserine Oxidation During Apoptosis
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    Chapter -1592597947 Quantitative Method of Measuring Phosphatidylserine Externalization During Apoptosis Using Electron Paramagnetic Resonance Spectroscopy and Annexin-Conjugated Iron
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    Chapter -1592597939 Detection of Programmed Cell Death in Cells Exposed to Genotoxic Agents Using a Caspase Activation Assay