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Mitochondrial Medicine

Overview of attention for book
Cover of 'Mitochondrial Medicine'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 1 DQAsomes as the Prototype of Mitochondria-Targeted Pharmaceutical Nanocarriers: Preparation, Characterization, and Use
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    Chapter 2 Predicting Mitochondrial Targeting by Small Molecule Xenobiotics Within Living Cells Using QSAR Models
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    Chapter 3 Mitochondrial Medicine
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    Chapter 4 Synthesis of Triphenylphosphonium Phospholipid Conjugates for the Preparation of Mitochondriotropic Liposomes
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    Chapter 5 Synthesis and Evaluation of 18 F-Labeled Fluoroalkyl Triphenylphosphonium Salts as Mitochondrial Voltage Sensors in PET Myocardial Imaging
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    Chapter 6 Bridging the Gap Between Nature and Antioxidant Setbacks: Delivering Caffeic Acid to Mitochondria
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    Chapter 7 Mitochondriotropic Nanoemulsified Genistein-Loaded Vehicles for Cancer Therapy
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    Chapter 8 Formulation and Optimization of Mitochondria-Targeted Polymeric Nanoparticles
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    Chapter 9 Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells.
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    Chapter 10 Targeting the Mitochondrial Genome via a Dual Function MITO-Porter: Evaluation of mtDNA Levels and Mitochondrial Function
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    Chapter 11 Mitochondrial, Acidic, and Cytosolic pHs Determination by 31 P NMR Spectroscopy: Design of New Sensitive Targeted pH Probes
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    Chapter 12 Methodology for Use of Mitochondria-Targeted Cations in the Field of Oxidative Stress-Related Research
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    Chapter 13 Synthesis and Testing of Novel Isomeric Mitochondriotropic Derivatives of Resveratrol and Quercetin
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    Chapter 14 Evaluation of Respiration of Mitochondria in Cancer Cells Exposed to Mitochondria-Targeted Agents
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    Chapter 15 The Effect of Mitochondrially Targeted Anticancer Agents on Mitochondrial (Super)Complexes
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    Chapter 16 Mitochondrial Targeting of Recombinant RNA
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    Chapter 17 Mitochondrial Targeting of Catalytic RNAs
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    Chapter 18 Allotopic Expression of ATP6 in the Mouse as a Transgenic Model of Mitochondrial Disease
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    Chapter 19 Analysis of pollutant-induced changes in mitochondrial DNA methylation.
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    Chapter 20 ETS and DEAS Studies of the Reduction of Xenobiotics in Mitochondrial Intermembrane Space
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    Chapter 21 Analysis of Mitochondrial Morphology and Function Under Conditions of Mitofusin 2 Deficiency
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    Chapter 22 Yeast as a tool to study mitochondrial retrograde pathway en route to cell stress response.
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    Chapter 23 Cell Energy Budget Platform for Assessment of Cell Metabolism
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    Chapter 24 Induced Pluripotent Stem Cells (iPSCs) for Modeling Mitochondrial DNA Disorders
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    Chapter 25 Cytoplasmic Transfer Methods for Studying the Segregation of Mitochondrial DNA in Mice
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    Chapter 26 In Vivo Visualization and Quantification of Mitochondrial Morphology in C. elegans
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    Chapter 27 Mitochondrial DNA as a Biosensor of UV Exposure in Human Skin
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    Chapter 28 Assessment of Short- and Medium-Chain Fatty Acids on Mitochondrial Function in Severe Inflammation
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    Chapter 29 Atomic Force Microscopy-Based Shape Analysis of Heart Mitochondria
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    Chapter 30 Enzymatic Assays for Probing Mitochondrial Apoptosis
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    Chapter 31 A cybrid cell model for the assessment of the link between mitochondrial deficits and sporadic Parkinson's disease.
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    Chapter 32 Analysis of mitochondrial network by imaging: proof of technique in schizophrenia.
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    Chapter 33 Erratum
Attention for Chapter 22: Yeast as a tool to study mitochondrial retrograde pathway en route to cell stress response.
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Chapter title
Yeast as a tool to study mitochondrial retrograde pathway en route to cell stress response.
Chapter number 22
Book title
Mitochondrial Medicine
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-2288-8_22
Pubmed ID
25634284
Book ISBNs
978-1-4939-2287-1, 978-1-4939-2288-8
Authors

Maša Ždralević, Nicoletta Guaragnella, Sergio Giannattasio, Ždralević, Maša, Guaragnella, Nicoletta, Giannattasio, Sergio

Abstract

Mitochondrial retrograde signaling is a mitochondria-to-nucleus communication pathway, conserved from yeast to humans, by which dysfunctional mitochondria relay signals that lead to cell stress adaptation in physiopathological conditions by changes in nuclear gene expression. The best comprehension of components and regulation of retrograde signaling have been obtained in Saccharomyces cerevisiae, where retrograde target gene expression is regulated by RTG genes. In this chapter, we describe the methods to measure mitochondrial retrograde pathway activation in yeast cells by monitoring the mRNA levels of RTG target genes, such as those encoding for peroxisomal citrate synthase, aconitase, and NAD(+)-specific isocitrate dehydrogenase subunit 1, as well as the phosphorylation status of Rtg1/3p transcriptional factor which controls RTG target gene transcription.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 33%
Student > Bachelor 2 13%
Professor 2 13%
Student > Master 2 13%
Student > Ph. D. Student 1 7%
Other 3 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 53%
Biochemistry, Genetics and Molecular Biology 5 33%
Business, Management and Accounting 1 7%
Unknown 1 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2015.
All research outputs
#20,252,875
of 22,782,096 outputs
Outputs from Methods in molecular biology
#9,885
of 13,094 outputs
Outputs of similar age
#295,685
of 352,967 outputs
Outputs of similar age from Methods in molecular biology
#635
of 996 outputs
Altmetric has tracked 22,782,096 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,094 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 996 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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