Current Topics in Microbiology and Immunology. New volume edited by Holger Barth: Uptake and Trafficking of Protein Toxins https://t.co/TqvBl5suwZ #springerlink
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Clostridial Binary Toxins: Basic Understandings that Include Cell Surface Binding and an Internal “Coup de Grâce”, via Current Topics in Microbiology and Immunology https://t.co/YOMeGznP8g
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Toxins A and B from Clostridium difficile (TcdA, TcdB) are huge single-chain but multidomain proteins that display redundant binding domains via a complex uptake process leading to intracellular interaction with the cytosol of host cells https://t.co/DMB8H
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Botulinum neurotoxins (BoNT) pass through the intestinal epithelial barrier mainly via a transcytotic mechanism and then diffuses or is transported to the neuromuscular junctions by the lymph or blood circulation. https://t.co/4foYPouDMJ