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TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease

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Cover of 'TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction: How We Encountered TCTP and Our Purpose in Studying It
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    Chapter 2 Structural Insights into TCTP and Its Interactions with Ligands and Proteins
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    Chapter 3 Structure-Function Relationship of TCTP
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    Chapter 4 The Translational Controlled Tumour Protein TCTP: Biological Functions and Regulation
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    Chapter 5 Current Understanding of the TCTP Interactome
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    Chapter 6 Role and Fate of TCTP in Protein Degradative Pathways
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    Chapter 7 Roles of the Translationally Controlled Tumor Protein (TCTP) in Plant Development
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    Chapter 8 Function of Translationally Controlled Tumor Protein in Organ Growth: Lessons from Drosophila Studies
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    Chapter 9 Translationally Controlled Tumor Protein (TCTP/HRF) in Animal Venoms
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    Chapter 10 Tctp in Neuronal Circuitry Assembly
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    Chapter 11 Elusive Role of TCTP Protein and mRNA in Cell Cycle and Cytoskeleton Regulation
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    Chapter 12 The Translationally Controlled Tumor Protein and the Cellular Response to Ionizing Radiation-Induced DNA Damage
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    Chapter 13 TCTP Has a Crucial Role in the Different Stages of Prostate Cancer Malignant Progression
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    Chapter 14 Role of TCTP for Cellular Differentiation and Cancer Therapy
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    Chapter 15 Targeting TCTP with Sertraline and Thioridazine in Cancer Treatment
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    Chapter 16 History of Histamine-Releasing Factor (HRF)/Translationally Controlled Tumor Protein (TCTP) Including a Potential Therapeutic Target in Asthma and Allergy
Attention for Chapter 6: Role and Fate of TCTP in Protein Degradative Pathways
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Chapter title
Role and Fate of TCTP in Protein Degradative Pathways
Chapter number 6
Book title
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease
Published in
Results and problems in cell differentiation, January 2017
DOI 10.1007/978-3-319-67591-6_6
Pubmed ID
Book ISBNs
978-3-31-967590-9, 978-3-31-967591-6
Authors

Michel Vidal, Vidal, Michel

Abstract

This chapter focuses on published studies specifically concerning TCTP and its involvement in degradation or stabilization of various proteins, and also in its own degradation in different ways. The first part relates to the inhibition of proteasomal degradation of proteins. This can be achieved by masking ubiquitination sites of specific partners, by favoring ubiquitin E3 ligase degradation, or by regulating proteasome activity. The second part addresses the ability of TCTP to favor degradation of specific proteins through proteasome or macroautophagic pathways. The third part discusses about the different ways by which TCTP has been shown to be degraded.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 67%
Student > Ph. D. Student 1 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 33%
Agricultural and Biological Sciences 1 33%
Immunology and Microbiology 1 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2019.
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#20,453,782
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Outputs from Results and problems in cell differentiation
#163
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Outputs of similar age
#356,212
of 421,290 outputs
Outputs of similar age from Results and problems in cell differentiation
#27
of 39 outputs
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