Chapter title |
Mycobacterium tuberculosis Complex Members Adapted to Wild and Domestic Animals. - PubMed - NCBI
|
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Chapter number | 7 |
Book title |
Strain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control
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Published in |
Advances in experimental medicine and biology, November 2017
|
DOI | 10.1007/978-3-319-64371-7_7 |
Pubmed ID | |
Book ISBNs |
978-3-31-964369-4, 978-3-31-964371-7
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Authors |
Malone, Kerri M., Gordon, Stephen V., Kerri M. Malone, Stephen V. Gordon |
Abstract |
The Mycobacterium tuberculosis complex (MTBC) is composed of several highly genetically related species that can be broadly classified into those that are human-host adapted and those that possess the ability to propagate and transmit in a variety of wild and domesticated animals. Since the initial description of the bovine tubercle bacillus, now known as Mycobacterium bovis, by Theobald Smith in the late 1800's, isolates originating from a wide range of animal hosts have been identified and characterized as M. microti, M. pinnipedii, the Dassie bacillus, M. mungi, M. caprae, M. orygis and M. suricattae. This chapter outlines the events resulting in the identification of each of these animal-adapted species, their close genetic relationships, and how genome-based phylogenetic analyses of species-specific variation amongst MTBC members is beginning to unravel the events that resulted in the evolution of the MTBC and the observed host tropism between the human- and animal-adapted member species. |
X Demographics
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United Kingdom | 5 | 33% |
Ireland | 2 | 13% |
Spain | 1 | 7% |
Mexico | 1 | 7% |
Argentina | 1 | 7% |
India | 1 | 7% |
Unknown | 4 | 27% |
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Members of the public | 6 | 40% |
Mendeley readers
Geographical breakdown
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Unknown | 128 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 15 | 12% |
Researcher | 14 | 11% |
Student > Master | 14 | 11% |
Student > Doctoral Student | 10 | 8% |
Student > Postgraduate | 9 | 7% |
Other | 25 | 20% |
Unknown | 41 | 32% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 17 | 13% |
Biochemistry, Genetics and Molecular Biology | 16 | 13% |
Immunology and Microbiology | 13 | 10% |
Medicine and Dentistry | 8 | 6% |
Other | 9 | 7% |
Unknown | 46 | 36% |