Chapter title |
Bioprinting and Biofabrication with Peptide and Protein Biomaterials
|
---|---|
Chapter number | 5 |
Book title |
Peptides and Peptide-based Biomaterials and their Biomedical Applications
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-3-319-66095-0_5 |
Pubmed ID | |
Book ISBNs |
978-3-31-966094-3, 978-3-31-966095-0
|
Authors |
Mitchell Boyd-Moss, Kate Fox, Milan Brandt, David Nisbet, Richard Williams, Boyd-Moss, Mitchell, Fox, Kate, Brandt, Milan, Nisbet, David, Williams, Richard |
Abstract |
The ability to fabricate artificial tissue constructs through the controlled organisation of cells, structures and signals within a biomimetic scaffold offers significant promise to the field of regenerative medicine, drug delivery and tissue engineering. Advances in additive manufacturing technologies have facilitated the printing of spatially defined cell-laden artificial tissue constructs capable of providing biomimetic spatiotemporal presentation of biological and physical cues to cells in a designed multicomponent structure. Despite significant progress in the field of bioprinting, a key challenge remains in developing and utilizing materials that can adequately recapitulate the complexities of the native extracellular matrix on a nanostructured, chemical level during the printing process. This gives rise to the need for suitable materials - particularly in establishing effective control over cell fate, tissue vascularization and innervation. Recently, significant interested has been invested into developing candidate materials using protein and peptide-derived biomaterials. The ability of these materials to form highly printable hydrogels which are reminiscent of the native ECM has seen significant use in a variety of regenative applications, including both organ bioprinting and non-organ bioprinting. Here, we discuss the emerging technologies for peptide-based bioprinting applications, highlighting bioink development and detailing bioprinter processors. Furthermore, this work presents application specific, peptide-based bioprinting approaches, and provides insight into current limitations and future perspectives of peptide-based bioprinting techniques. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 50% |
United States | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 51 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 12 | 24% |
Researcher | 6 | 12% |
Student > Bachelor | 5 | 10% |
Student > Doctoral Student | 4 | 8% |
Student > Master | 4 | 8% |
Other | 5 | 10% |
Unknown | 15 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 11 | 22% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Medicine and Dentistry | 5 | 10% |
Materials Science | 5 | 10% |
Chemistry | 3 | 6% |
Other | 5 | 10% |
Unknown | 17 | 33% |