Chapter title |
Reactive Oxygen Species, Granulocytes, and NETosis.
|
---|---|
Chapter number | 12 |
Book title |
Respiratory Virology and Immunogenicity
|
Published in |
Advances in experimental medicine and biology, October 2014
|
DOI | 10.1007/5584_2014_12 |
Pubmed ID | |
Book ISBNs |
978-3-31-910017-3, 978-3-31-910018-0
|
Authors |
Araźna M, Pruchniak MP, Demkow U, Magdalena Araźna, Michał P. Pruchniak, Urszula Demkow, Araźna, Magdalena, Pruchniak, Michał P., Demkow, Urszula |
Abstract |
When pathogens invade the body, neutrophils create the first line of defense. Basic weaponry consists of phagocytosis and degranulation, but these cells have yet another ace in the sleeve, a unique strategy in which invading microorganisms are being destroyed. These cellular warriors are able to release nuclear chromatin and form extracellular structure, known as neutrophil extracellular traps (NET). NET formation is connected with the presence of free radicals. Research has shown that inhibition of free radical formation leads to suppression of NET release. The exact mechanisms controlling cooperation of free radicals with NET still remain unclear. New investigations in this field may contribute to discovery of NET etiology and put a new light on related disorders. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Poland | 1 | 3% |
Unknown | 30 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 23% |
Student > Ph. D. Student | 7 | 23% |
Student > Master | 3 | 10% |
Student > Postgraduate | 3 | 10% |
Researcher | 2 | 6% |
Other | 2 | 6% |
Unknown | 7 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 35% |
Medicine and Dentistry | 3 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Immunology and Microbiology | 2 | 6% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Other | 2 | 6% |
Unknown | 9 | 29% |