Chapter 1 The history of bipolar disorders

Chapter 2 The clinical diagnosis of bipolar depression

Chapter 4 Suicide and bipolar disorder

Chapter 5 The genetic basis of bipolar disorder

Chapter 6 Understanding the neurobiology of bipolar depression

Chapter 7 Non-pharmacological treatments and chronobiological aspects of bipolar disorder: implications for novel therapeutics

Chapter 8 Neuroimaging studies of bipolar depression: therapeutic implications

Chapter 9 Pharmacological treatment of acute bipolar depression

Chapter 10 Pharmacological treatment of the maintenance phase of bipolar depression: focus on relapse prevention studies and the impact of design on generalizability

Chapter 11 Non-pharmacological somatic treatments for bipolar depression

Chapter 12 Potential novel treatments for bipolar depression

Chapter 13 Late-onset bipolar disorder

Chapter 14 Treatment of childhood-onset bipolar disorder

Chapter 15 Treatment of bipolar disorder during and after pregnancy

Chapter 16 Conclusion