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The Search for Anti-Inflammatory Drugs

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Cover of 'The Search for Anti-Inflammatory Drugs'

Table of Contents

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    Book Overview
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    Chapter 1 The Discovery of Drugs to Treat Arthritis: A Historical View
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    Chapter 2 The History of the Discovery and Development of Cyclosporine (Sandimmune®)
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    Chapter 3 Discovery and Development of FK506 (Tacrolimus), A Potent Immunosuppressant of Microbial Origin
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    Chapter 4 Discovery of Sulindac, a Reversible Prodrug, as a Second-Generation Indomethacin
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    Chapter 5 The Discovery of Zileuton (Leutrol®)
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    Chapter 6 Discovery of Accolate™ (ICI 204,219), a Peptide Leukotriene Antagonist for Asthma
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    Chapter 7 Discovery of ZD2138, a Potent, Selective, Well-Tolerated, Nonredox Inhibitor of the Enzyme 5-Lipoxygenase
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    Chapter 8 Development of MK 0591: An Orally Active Leukotriene Biosynthesis Inhibitor with a Novel Mechanism of Action
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    Chapter 9 Discovery of BIRM 270: A New Class of Leukotriene Biosynthesis Inhibitors
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    Chapter 10 Discovery and Development of the Immunomodulatory Azaspiranes
Attention for Chapter 7: Discovery of ZD2138, a Potent, Selective, Well-Tolerated, Nonredox Inhibitor of the Enzyme 5-Lipoxygenase
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