Chapter 1 Kuru: Introduction to Prion Diseases

Chapter 2 Anthropological Methods Used in Kuru Research

Chapter 3 Nonhuman Primates in Research on Transmissible Spongiform Encephalopathies

Chapter 4 Clinical Features and Diagnosis of Human Prion Diseases

Chapter 5 Neuropathology, Immunohistochemistry, and Biochemistry in Human Prion Diseases

Chapter 6 Subcellular and Molecular Changes Associated with Abnormal PrP Accumulation in Brain and Viscera of Classical and Atypical Prion Diseases

Chapter 7 Electron Microscopy of Prion Diseases

Chapter 8 Cell Death and Autophagy in Prion Diseases

Chapter 9 Methods for Isolation of Spiroplasma sp. from Prion-Positive Eye Tissues of Sheep Affected with Terminal Scrapie

Chapter 11 Analysis of Charge Isoforms of the Scrapie Prion Protein Using Two-Dimensional Electrophoresis

Chapter 12 Exosomes in Prion Diseases

Chapter 13 Synthetic Mammalian Prions

Chapter 14 Biomarkers in Cerebrospinal Fluid

Chapter 15 The Use of Transgenic and Knockout Mice in Prion Research

Chapter 16 Transgenic Mouse Models of Prion Diseases