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Histamine and Histamine Receptors in Health and Disease

Overview of attention for book
Cover of 'Histamine and Histamine Receptors in Health and Disease'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 8 Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia
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    Chapter 9 Histamine and Histamine Receptors in Allergic Dermatitis
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    Chapter 10 Structural Analysis of the Histamine H1 Receptor
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    Chapter 11 Role of the Histamine H4-Receptor in Bronchial Asthma
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    Chapter 12 Role of the Histamine H3 Receptor in the Central Nervous System
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    Chapter 13 Histamine Clearance Through Polyspecific Transporters in the Brain
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    Chapter 14 Histamine H1 Receptor Gene Expression and Drug Action of Antihistamines
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    Chapter 15 Regulation of the Cardiovascular System by Histamine
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    Chapter 18 Histamine Release from Mast Cells and Basophils
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    Chapter 22 Analytical Methods for the Quantification of Histamine and Histamine Metabolites
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    Chapter 54 Histamine Food Poisoning.
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    Chapter 85 Allergy, Histamine and Antihistamines
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    Chapter 113 Molecular Modelling Approaches for the Analysis of Histamine Receptors and Their Interaction with Ligands
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    Chapter 124 Pharmacological Characterization of Human Histamine Receptors and Histamine Receptor Mutantsin the Sf9 Cell Expression System
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    Chapter 125 Changes in Histidine Decarboxylase, Histamine N-Methyltransferase and Histamine Receptors in Neuropsychiatric Disorders
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    Chapter 127 Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Related Conditions
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    Chapter 130 Clinical Development of Histamine H4 Receptor Antagonists
Attention for Chapter 11: Role of the Histamine H4-Receptor in Bronchial Asthma
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Chapter title
Role of the Histamine H4-Receptor in Bronchial Asthma
Chapter number 11
Book title
Histamine and Histamine Receptors in Health and Disease
Published in
Handbook of experimental pharmacology, January 2016
DOI 10.1007/164_2016_11
Pubmed ID
Book ISBNs
978-3-31-958192-7, 978-3-31-958194-1
Authors

Detlef Neumann

Abstract

Histamine is a pro-inflammatory mediator with a prominent role in allergic diseases. Antagonists at the histamine receptor subtype 1 are central in anti-allergic therapies, with the exception of allergic asthma, where they are clinically without effect. The latest identified histamine receptor subtype 4, which is expressed mainly in hematopoietic cells, now provides a reasonable target for new therapeutic strategies inhibiting histamine function. The pathophysiology of allergy, esp. allergic asthma, and in its context the effects of antagonists at the histamine receptor subtype 4 in preclinical and clinical settings are discussed in this chapter.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 13%
Student > Bachelor 2 13%
Other 1 6%
Lecturer 1 6%
Student > Doctoral Student 1 6%
Other 2 13%
Unknown 7 44%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 2 13%
Biochemistry, Genetics and Molecular Biology 2 13%
Chemistry 2 13%
Medicine and Dentistry 1 6%
Engineering 1 6%
Other 0 0%
Unknown 8 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2017.
All research outputs
#15,478,452
of 23,001,641 outputs
Outputs from Handbook of experimental pharmacology
#399
of 647 outputs
Outputs of similar age
#232,121
of 394,589 outputs
Outputs of similar age from Handbook of experimental pharmacology
#42
of 55 outputs
Altmetric has tracked 23,001,641 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 647 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,589 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.