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Handbook on Immunosenescence

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Cover of 'Handbook on Immunosenescence'

Table of Contents

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    Book Overview
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    Chapter 1 The Immune Risk Profile and Associated Parameters in Late Life: Lessons from the OCTO and NONA Longitudinal Studies
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    Chapter 2 Lymphocytes Sub-Types and Functions in Centenarians as Models for Successful Ageing
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    Chapter 3 Mouse Models and Genetics of Immunosenescence
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    Chapter 4 Insect Models of Immunosenescence
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    Chapter 5 Clonal Culture Models of T-cell Senescence
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    Chapter 6 Mouse Models of Influenza
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    Chapter 7 A Transgenic Dwarf Rat Strain as a Tool for the Study of Immunosenescence in Aging Rats and the Effect of Calorie Restriction
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    Chapter 8 Mathematical Modeling of Immunosenescence: Scenarios, Processes and Limitations
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    Chapter 9 Age, T-cell Homeostasis, and T-cell Diversity in Humans
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    Chapter 10 The Role of T-regulatory Cells in Immune Senescence
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    Chapter 11 Age-related Changes in Subpopulations of Peripheral Blood Lymphocytes in Healthy Japanese Population
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    Chapter 12 Age-associated T-cell Clonal Expansions (TCE) in vivo—Implications for Pathogen Resistance
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    Chapter 13 T-cell Cycle and Immunosenescence: Role of Aging in the T-cell Proliferative Behaviour and Status Quo Maintenance
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    Chapter 14 Mismatch Repair System and Aging: Microsatellite Instability in Peripheral Blood Cells of the Elderly and in the T-cell Clone Longitudinal Model
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    Chapter 15 Activation-Induced Cell Death of T-Cells in Elderly
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    Chapter 16 CD8 Clonal Expansions in Mice: An Age-associated Alteration of CD8 Memory T-cells
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    Chapter 17 Generation and Gene Expression of CD28-CD8 T-cells in Human
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    Chapter 18 Role of Regulatory Subsets During Aging
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    Chapter 19 Transcription Factors in Mature B-Cells During Aging
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    Chapter 20 B-Cell Repertoire Changes in Mouse Models of Aging
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    Chapter 21 B-Cells and Antibodies in Old Humans
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    Chapter 22 Neutrophil Granulocyte Functions in the Elderly
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    Chapter 23 Signal Transduction Changes in fMLP, TLRs, TREM-1 and GM-CSF Receptors in PMN with Aging
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    Chapter 24 Synergistic Effects of Ageing and Stress on Neutrophil Function
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    Chapter 25 Role of Dendritic Cells in Aging
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    Chapter 26 Phenotypic and Functional Changes of Circulating Monocytes in Elderly
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    Chapter 27 NK Cells in Human Ageing
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    Chapter 28 Natural Killer Cells and Human Longevity
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    Chapter 29 The Effects of Age on CD1d-restricted NKT-cells and Their Contribution to Peripheral T-cell Immunity
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    Chapter 30 Lympho-Hematopoietic Stem Cells and Their Aging
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    Chapter 31 Implications of Developmental Switches for Hematopoietic Stem Cell Aging
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    Chapter 32 Associations of Cytokine Polymorphisms with Immunosenescence
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    Chapter 33 Cytokine Polymorphisms and Immunosenescence
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    Chapter 34 Role of TLR Polymorphisms in Immunosenescence
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    Chapter 35 Signal Transduction Changes in T-cells with Aging
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    Chapter 36 Molecular Signaling of CD95- and TNFR-Mediatedapoptosis in Naïve and Various Memory Subsets of T-Cells
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    Chapter 37 Mitochondria and Immunosenescence
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    Chapter 38 Proteasome Activity and Immunosenescence
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    Chapter 39 Age-Related Changes in Type 1 and Type 2 Cytokine Production in Humans
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    Chapter 40 Cytokine Expression and Production Changes in Very Old Age
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    Chapter 41 Neuro-Endocrine-Immune Network and its Age-Related Changes
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    Chapter 42 Sex Hormones and Immunosenescence
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    Chapter 43 Glucocorticoids and DHEA: Do They Have a Role in Immunosenescence?
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    Chapter 44 Thymic Involution and Thymic Renewal
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    Chapter 45 Inflamm-Aging
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    Chapter 46 Molecular and Cellular Aspects of Macrophage Aging
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    Chapter 47 Aging and HIV Disease: Synergistic Immunological Effects?
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    Chapter 48 Role of Immunosenescence in Infections and Sepsis in the Elderly
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    Chapter 49 Beneficial and Detrimental Manifestations of Age on CD8 + T-Cell Memory to Respiratory Pathogens
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    Chapter 50 HIV Infection as a Model of Accelerated Immunosenescence
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    Chapter 51 Autoimmunity and Autoimmune Diseases in the Elderly
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    Chapter 52 Autoimmunity—Aging Mouse Model for Autoimmune Diseases
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    Chapter 53 Atherosclerosis—An Age-dependent Autoimmune Disease
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    Chapter 54 Immuno-Inflammatory Athero-Arteriosclerosis Induced by Elastin Peptides. Effect of Age
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    Chapter 55 Aging, Immunity and Cancer
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    Chapter 56 Breast Cancer and Immunosenescence
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    Chapter 57 Aging, Cancer and Apoptosis in Animal Models and Clinical Settings
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    Chapter 58 Her-2/neu Transgenic Mice for Evaluation of Immune and Antitumor Responses Against Self-Tumor Antigens in the Young and the Old
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    Chapter 59 Cancer Immunotherapy and Aging: Lessons From the Mouse
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    Chapter 60 Insulin Resistance, Chronic Inflammation and the Link with Immunosenescence
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    Chapter 61 Decline of Immune Responsiveness: A Pathogenetic Factor in Alzheimer’s Disease?
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    Chapter 62 Inflammatory Markers and Frailty
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    Chapter 63 CMV Infection and Frailty: Immunologic Consequences and Disease Pathogenesis
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    Chapter 64 Osteoporosis, Inflammation and Ageing
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    Chapter 65 Protein-Energy Malnutrition as a Determinant for Immuno-Senescence
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    Chapter 66 Role of Zinc and Selenium in Oxidative Stress and Immunosenescence: Implications for Healthy Ageing and Longevity
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    Chapter 67 Immunomoduation by Polyunsaturated Fatty Acids: Impact on T-cell Functions and Signaling
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    Chapter 68 Omega-3 Polyunsaturated Fatty Acids and Immunosenescence
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    Chapter 69 Effect of Intrinsic and Extrinsic Lipids on T-cell Signalling
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    Chapter 70 Effect of Anti-influenza Vaccination on Immune System in the Elderly
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    Chapter 71 Immunosenescence Modulation by Vaccination
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    Chapter 72 Interleukin -7 and Immunorejuvenation
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    Chapter 73 Assessment of Age-related Decline of Immunological Function and Possible Methods for Immunological Restoration in Elderly
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    Chapter 74 Thymic Regeneration in Mice and Humans Following Sex Steroid Ablation
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    Chapter 75 Nutraceuticals and Immune Restoration in the Elderly
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    Chapter 76 Gene Therapy and Immune Senescence
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    Chapter 77 Perspectives: Is Immunosenescence Clinically Relevant?
Overall attention for this book and its chapters
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Mentioned by

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Citations

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Readers on

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Title
Handbook on Immunosenescence
Published by
Springer Netherlands, February 2009
DOI 10.1007/978-1-4020-9063-9
ISBNs
978-1-4020-9062-2, 978-1-4020-9063-9
Editors

Fulop, Tamas, Franceschi, Claudio, Hirokawa, Katsuiku, Pawelec, Graham

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 2%
Unknown 41 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 17%
Researcher 6 14%
Student > Master 5 12%
Other 4 10%
Professor 3 7%
Other 9 21%
Unknown 8 19%
Readers by discipline Count As %
Medicine and Dentistry 10 24%
Agricultural and Biological Sciences 7 17%
Biochemistry, Genetics and Molecular Biology 6 14%
Immunology and Microbiology 4 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 5 12%
Unknown 8 19%