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Overview of attention for book
Cover of 'Methylxanthines'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Notes on the History of Caffeine Use
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    Chapter 2 Distribution, biosynthesis and catabolism of methylxanthines in plants.
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    Chapter 3 Pharmacokinetics and Metabolism of Natural Methylxanthines in Animal and Man
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    Chapter 4 Inhibition of Cyclic Nucleotide Phosphodiesterases by Methylxanthines and Related Compounds
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    Chapter 5 Methylxanthines and Ryanodine Receptor Channels
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    Chapter 6 Xanthines as Adenosine Receptor Antagonists
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    Chapter 7 Theobromine and the Pharmacology of Cocoa
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    Chapter 8 Propentofylline: Glial Modulation, Neuroprotection, and Alleviation of Chronic Pain
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    Chapter 9 Methylxanthines, Seizures, and Excitotoxicity
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    Chapter 10 Impacts of Methylxanthines and Adenosine Receptors on Neurodegeneration: Human and Experimental Studies
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    Chapter 11 Methylxanthines and Pain
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    Chapter 12 Methylxanthines and Sleep
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    Chapter 13 Methylxanthines and Reproduction
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    Chapter 14 Methylxanthines During Pregnancy and Early Postnatal Life
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    Chapter 15 Methylxanthines and the Kidney
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    Chapter 16 Methylxanthines
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    Chapter 17 Methylxanthines in Asthma
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    Chapter 18 Methylxanthines and Inflammatory Cells
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    Chapter 19 Methylxanthines, Inflammation, and Cancer: Fundamental Mechanisms
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    Chapter 20 Methylxanthines and Drug Dependence: A Focus on Interactions with Substances of Abuse
  22. Altmetric Badge
    Chapter 21 Methylxanthines and Human Health: Epidemiological and Experimental Evidence
Attention for Chapter 7: Theobromine and the Pharmacology of Cocoa
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#9 of 689)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

18 news outlets
4 blogs
1 X user
1 Facebook page
5 Wikipedia pages


48 Dimensions

Readers on

262 Mendeley
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Chapter title
Theobromine and the Pharmacology of Cocoa
Chapter number 7
Book title
Published in
Handbook of experimental pharmacology, January 2011
DOI 10.1007/978-3-642-13443-2_7
Pubmed ID
Book ISBNs
978-3-64-213442-5, 978-3-64-213443-2

Hendrik Jan Smit, Smit HJ, Smit, Hendrik Jan


The effects of theobromine in man are underresearched, possibly owing to the assumption that it is behaviourally inert. Toxicology research in animals may appear to provide alarming results, but these cannot be extrapolated to humans for a number of reasons. Domestic animals and animals used for racing competitions need to be guarded from chocolate and cocoa-containing foods, including foods containing cocoa husks. Research ought to include caffeine as a comparative agent, and underlying mechanisms need to be further explored. Of all constituents proposed to play a role in our liking for chocolate, caffeine is the most convincing, though a role for theobromine cannot be ruled out. Most other substances are unlikely to exude a psychopharmacological effect owing to extremely low concentrations or the inability to reach the blood-brain barrier, whilst chocolate craving and addiction need to be explained by means of a culturally determined ambivalence towards chocolate.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 262 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Colombia 1 <1%
Germany 1 <1%
Sweden 1 <1%
South Africa 1 <1%
India 1 <1%
Brazil 1 <1%
Spain 1 <1%
Slovenia 1 <1%
Other 2 <1%
Unknown 249 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 43 16%
Student > Master 40 15%
Student > Ph. D. Student 36 14%
Researcher 33 13%
Student > Doctoral Student 14 5%
Other 41 16%
Unknown 55 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 38 15%
Medicine and Dentistry 38 15%
Engineering 16 6%
Chemistry 14 5%
Biochemistry, Genetics and Molecular Biology 10 4%
Other 86 33%
Unknown 60 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 168. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2024.
All research outputs
of 25,775,807 outputs
Outputs from Handbook of experimental pharmacology
of 689 outputs
Outputs of similar age
of 192,586 outputs
Outputs of similar age from Handbook of experimental pharmacology
of 25 outputs
Altmetric has tracked 25,775,807 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 689 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,586 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.