Chapter 1 Antimutagenesis Studies in Japan

Chapter 2 Cancer Prevention: Underlying Principles and Practical Proposals

Chapter 3 Anticlastogenic Dietary Factors Assessed in Mammalian Assays

Chapter 4 Antigenotoxic Activity of Carotenoids in Carcinogen-Exposed Populations

Chapter 5 Plant Antimutagens

Chapter 6 Human Biomonitoring in Exposure to Environmental Genotoxicants

Chapter 7 The Concept of Activity Profiles of Antimutagens

Chapter 8 Prevention of Formation of Important Mutagens/Carcinogens in the Human Food Chain

Chapter 9 Free Radical Reactions with DNA and Its Nucleotides

Chapter 10 Mechanisms of Inactivation of Oxygen Radicals by Dietary Antioxidants and Their Models

Chapter 11 Role of Dietary Antioxidants in Protection against Oxidative Damage

Chapter 12 Inhibition of Carcinogenesis by Naturally-Occurring and Synthetic Compounds

Chapter 13 Newly Recognized Anticarcinogenic Fatty Acids

Chapter 14 Caloric Restriction in Experimental Carcinogenesis

Chapter 15 Carcinogenicity and Modification of Carcinogenic Response by Antioxidants

Chapter 16 Inhibition of Tumor Promotion by DL-α-Difluoromethylornithine, A Specific Irreversible Inhibitor of Ornithine Decarboxylase

Chapter 17 New Antitumor Promoters: (-)-Epigallocatechin Gallate and Sarcophytols A and B

Chapter 18 Chemoprevention of Mammary Cancer by Retinoids

Chapter 19 Suppression of Tumor Promotion by Inhibitors of Poly(ADP)Ribose Formation

Chapter 20 Antimutagenic Activity of Vitamins in Cultured Mammalian Cells

Chapter 21 Microcell-Mediated Chromosome Transfer: A Strategy for Studying the Genetics and Molecular Pathology of Human Hereditary Diseases with Abnormal Responses to DNA Damage

Chapter 22 Genetic Analyses of Cellular Functions Required for UV Mutagenesis in Escherichia Coli

Chapter 23 Position of a Single Acetylaminofluorene Adduct Within a Mutational Hot Spot is Critical for the Related Mutagenic Event

Chapter 24 Fidelity of Animal Cell DNA Polymerases α and δ and of a Human DNA Replication Complex

Chapter 25 Molecular Mechanisms of Replicational Fidelity in Escherichia Coli

Chapter 26 Permanent Conversion of NIH3T3 Cells Transformed by Activated c-Ha-ras, c-Ki-ras, N-ras, or c-raf, and of Human Pancreatic Adenocarcinoma Containing Activated c-Ki-ras to Apparently Normal Cells by Treatment with the Antibiotic Azatyrosine

Chapter 27 Oncogenes of Stomach Cancers

Chapter 28 Oncogenic Potential and Normal Function of the Proto-Oncogenes Encoding Protein-Tyrosine Kinases

Chapter 29 Inhibition of the Genotoxicity of 3-Amino-1-Methyl-5H- Pyrido[4,3-b]Indole (Trp-P-2) in Drosophila by Chlorophyll

Chapter 31 Proteolytic Activation of UmuD and MucA Proteins for SOS Mutagenesis

Chapter 32 Analysis of Bleomycin-Resistant DNA Synthesis in Cells from an Inherited Human Disorder, Ataxia Telangiectasia

Chapter 33 Tumor Dose-Response Studies with Aflatoxin B1 and the Ambivalent Modulator Indole-3-Carbinol: Inhibitory Versus Promotional Potency

Chapter 34 Antimutagenesis in Yeast by Sodium Chloride, Potassium Chloride, and Sodium Saccharin

Chapter 35 The Use of Drosophila as an in VIVO System to Study Modifiers of Chemical Mutagenesis

Chapter 36 The Mouse Mutant, “Wasted”: Tissue-Specific Radiation Sensitivity and Hematopoietic Cell Lineages

Chapter 37 Antimutagenic Effects of Tumor Promoters—Co-Mutagenic Effects of Co-Carcinogens

Chapter 38 Antimutagenic Effects of Dimethyl Sulfoxide on Metabolism and Genotoxicity of Benzene in Vivo

Chapter 39 Possible Antitumor Promoter in the Glandular Stomach: Calcium Chloride

Chapter 40 Reversion of Transformed NIH 3T3 Cells to Flat Cells by Inhibitors of Poly(ADP-ribose) Polymerase

Chapter 41 Inactivation of Mutagenic Heterocyclic and Aryl Amines by Linoleic Acid 13-Monohydroperoxide and Methemoglobin

Chapter 42 Establishment of a Highly Reproducible Transformation Assay of a Ras-Transfected Balb 3T3 Clone by Treatment with Promoters

Chapter 43 Antimutagenic Effect of umuD Mutant Plasmids: Isolation and Characterization of umuD Mutants Reduced in their Ability to Promote UV Mutagenesis in Escherichia Coli

Chapter 44 Antitumor-Promoting Activity of Sesquiterpene Isolated from an Herbal Spice

Chapter 45 Inhibitory Effects of Chlorogenic Acid, Reserpine, Polyprenoic Acid (E-5166), or Coffee on Hepatocarcinogenesis in Rats and Hamsters

Chapter 46 Antimutagenic Structure Modification of Quinoline: Fluorine-Substitution at Position-3

Chapter 47 Mutagenicity and Antimutagenicity of Thai Medicinal Plants

Chapter 48 Influence of Potential Antioxidants on Free-Radical Damage of Lymphocytes

Chapter 49 Specificity of Antimutagens against Chemical Mutagens in Microbial Systems

Chapter 50 Classification of Mechanisms of Inhibitors of Mutagenesis and Carcinogenesis

Chapter 51 Antimutagenic Effects of Chlorophyllin