Chapter title |
Development of Neural Activity in the Enteric Nervous System: Similarities and Differences to Other Parts of the Nervous System
|
---|---|
Chapter number | 5 |
Book title |
The Enteric Nervous System
|
Published in |
Advances in experimental medicine and biology, January 2016
|
DOI | 10.1007/978-3-319-27592-5_5 |
Pubmed ID | |
Book ISBNs |
978-3-31-927590-1, 978-3-31-927592-5
|
Authors |
Marlene M. Hao, M. Hao, Marlene |
Abstract |
All the neurons and glia of the enteric nervous system (ENS) arise from neural crest-derived cells that migrate into the gastrointestinal (GI) tract during development (Yntema and Hammond 1954; Le Douarin and Teillet 1973). Most of the ENS originates from vagal neural crest cells (NCCs), which arise from the caudal hindbrain region of the neural tube, adjacent to somites 1-7. In the developing mouse, vagal NCCs migrate into the developing oesophagus and stomach at embryonic day (E)9.5, enter the small intestine at E10.5, and colonise the developing GI tract in a rostral-to-caudal wave, reaching the anal end of the colon at E14.5 (Serbedzija et al. 1991; Kapur et al. 1992; Anderson et al. 2006). Recent evidence indicates that there is also trans-mesenteric migration of vagal NCCs, where some NCCs leave the small intestine and migrate directly across the mesentery into the colon (Nishiyama et al. 2012). Sacral NCCs also contribute to a small population of neurons and glia in the colon (Burns and Le Douarin 1998; Wang et al. 2011). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 33% |
Student > Master | 3 | 25% |
Student > Doctoral Student | 1 | 8% |
Student > Bachelor | 1 | 8% |
Unknown | 3 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 25% |
Neuroscience | 3 | 25% |
Agricultural and Biological Sciences | 2 | 17% |
Social Sciences | 1 | 8% |
Unknown | 3 | 25% |