Chapter title |
Properties and Immune Function of Cardiac Fibroblasts
|
---|---|
Chapter number | 3 |
Book title |
The Immunology of Cardiovascular Homeostasis and Pathology
|
Published in |
Advances in experimental medicine and biology, May 2017
|
DOI | 10.1007/978-3-319-57613-8_3 |
Pubmed ID | |
Book ISBNs |
978-3-31-957611-4, 978-3-31-957613-8
|
Authors |
Milena B. Furtado, Muneer Hasham |
Abstract |
This chapter will discuss the role of cardiac fibroblasts as a target of various immunological inputs as well as an immunomodulatory hub of the heart through interaction with immune cell types and chemokine or cytokine signaling. While the purpose of this chapter is to explore the immunomodulatory properties of cardiac fibroblasts, it is important to note that cardiac fibroblasts are not a homogeneous cell type, but have a unique embryological origin and molecular identity. Specific properties of cardiac fibroblasts may influence the way they interact with the heart microenvironment to promote healthy homeostatic function or respond to pathological insults. Therefore, we will briefly discuss these aspects of cardiac fibroblast biology and then focus on their immunomodulatory role in the heart. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 25% |
Student > Bachelor | 3 | 11% |
Student > Postgraduate | 2 | 7% |
Researcher | 2 | 7% |
Student > Ph. D. Student | 1 | 4% |
Other | 3 | 11% |
Unknown | 10 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 21% |
Biochemistry, Genetics and Molecular Biology | 3 | 11% |
Agricultural and Biological Sciences | 3 | 11% |
Immunology and Microbiology | 1 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 4% |
Other | 0 | 0% |
Unknown | 14 | 50% |