Chapter title |
Lymphocytes at the Heart of Wound Healing
|
---|---|
Chapter number | 11 |
Book title |
The Immunology of Cardiovascular Homeostasis and Pathology
|
Published in |
Advances in experimental medicine and biology, May 2017
|
DOI | 10.1007/978-3-319-57613-8_11 |
Pubmed ID | |
Book ISBNs |
978-3-31-957611-4, 978-3-31-957613-8
|
Authors |
Vânia Nunes-Silva, Stefan Frantz, Gustavo Campos Ramos |
Abstract |
The adult mammalian heart displays negligible regenerative capacity. Therefore, myocardial infarction (MI) often results in an irreversible loss of contractile tissue, leading to a collagenous scar formation, progressive remodelling and heart failure (HF). Over the past few years, emerging evidences indicate that a myocardial ischemic injury mobilizes not only sterile unspecific inflammation but also lymphocyte-mediated immune responses to cardiac auto-antigens. In the current chapter, we depict the infarcted heart as a "wounded" tissue and focus on the dynamic events leading to myocardial repair, with special emphasis on the role played by lymphocytes in this process. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 3 | 14% |
Student > Bachelor | 3 | 14% |
Student > Postgraduate | 3 | 14% |
Student > Master | 3 | 14% |
Student > Ph. D. Student | 2 | 10% |
Other | 2 | 10% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 19% |
Medicine and Dentistry | 4 | 19% |
Agricultural and Biological Sciences | 2 | 10% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Business, Management and Accounting | 1 | 5% |
Other | 2 | 10% |
Unknown | 7 | 33% |