Chapter title |
Ebolavirus: An Overview of Molecular and Clinical Pathogenesis
|
---|---|
Chapter number | 3 |
Book title |
Ebolaviruses
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7116-9_3 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7115-2, 978-1-4939-7116-9
|
Authors |
Veronica Vine, Dana P. Scott, Heinz Feldmann |
Editors |
Thomas Hoenen, Allison Groseth |
Abstract |
Ebolaviruses cause severe, often fatal hemorrhagic fever in Central, East, and West Africa. Until recently, they have been viewed as rare but highly pathogenic infections with regional, but limited, global public health impact. This view has changed with the emergence of the first epidemic of Ebola hemorrhagic fever in West Africa. In this chapter we provide an introduction of the pathogenesis of ebolaviruses as well as a description of clinical disease features. We also describe the current animal models used in ebolavirus research, detailing each model's unique strengths and weaknesses. We focus on Ebola virus representing the type species Zaire ebolavirus of the genus Ebolavirus, as most work relates to this pathogen. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 38% |
Student > Bachelor | 2 | 15% |
Professor > Associate Professor | 1 | 8% |
Student > Doctoral Student | 1 | 8% |
Unknown | 4 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 31% |
Agricultural and Biological Sciences | 2 | 15% |
Nursing and Health Professions | 1 | 8% |
Immunology and Microbiology | 1 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Other | 0 | 0% |
Unknown | 4 | 31% |