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Transcriptional Control of Lineage Differentiation in Immune Cells

Overview of attention for book
Cover of 'Transcriptional Control of Lineage Differentiation in Immune Cells'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 370 Genetic and Epigenetic Control of Early Lymphocyte Development.
  3. Altmetric Badge
    Chapter 371 Helper T Cell Plasticity: Impact of Extrinsic and Intrinsic Signals on Transcriptomes and Epigenomes
  4. Altmetric Badge
    Chapter 372 Transcriptional Regulatory Networks for CD4 T Cell Differentiation.
  5. Altmetric Badge
    Chapter 373 Transcriptional Control of Regulatory T cells
  6. Altmetric Badge
    Chapter 374 The Role of BTB-Zinc Finger Transcription Factors During T Cell Development and in the Regulation of T Cell-mediated Immunity.
  7. Altmetric Badge
    Chapter 375 Transcriptional Control of the Development and Function of Vα14i NKT Cells.
  8. Altmetric Badge
    Chapter 376 Transcriptional Control of NK Cell Differentiation and Function.
  9. Altmetric Badge
    Chapter 377 Transcriptional Control of Pre-B Cell Development and Leukemia Prevention
  10. Altmetric Badge
    Chapter 378 Transcriptional Control of Dendritic Cell Differentiation.
  11. Altmetric Badge
    Chapter 381 Transcription Factors Controlling Innate Lymphoid Cell Fate Decisions
Attention for Chapter 370: Genetic and Epigenetic Control of Early Lymphocyte Development.
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Chapter title
Genetic and Epigenetic Control of Early Lymphocyte Development.
Chapter number 370
Book title
Transcriptional Control of Lineage Differentiation in Immune Cells
Published in
Current topics in microbiology and immunology, May 2014
DOI 10.1007/82_2014_370
Pubmed ID
24850218
Book ISBNs
978-3-31-907394-1, 978-3-31-907395-8
Authors

Tomokatsu Ikawa

Editors

Wilfried Ellmeier, Ichiro Taniuchi

Abstract

T, B, and NK lymphocytes are generated from pluripotent hematopoietic stem cells through a successive series of lineage restriction processes. Many regulatory components, such as transcription factors, cytokines/cytokine receptors, and signal transduction molecules orchestrate cell fate specification and determination. In particular, transcription factors play a key role in regulating lineage-associated gene programs. Recent findings suggest the involvement of epigenetic factors in the maintenance of cell fate. Here, we review the early developmental events during lymphocyte lineage determination, focusing on the transcriptional networks and epigenetic regulation. Finally, we also discuss the developmental relationship between acquired and innate lymphoid cells.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Venezuela, Bolivarian Republic of 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 45%
Researcher 6 27%
Student > Master 2 9%
Student > Bachelor 2 9%
Professor > Associate Professor 1 5%
Other 1 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 45%
Biochemistry, Genetics and Molecular Biology 4 18%
Immunology and Microbiology 3 14%
Nursing and Health Professions 2 9%
Medicine and Dentistry 1 5%
Other 0 0%
Unknown 2 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2014.
All research outputs
#20,230,558
of 22,756,196 outputs
Outputs from Current topics in microbiology and immunology
#597
of 671 outputs
Outputs of similar age
#191,950
of 226,345 outputs
Outputs of similar age from Current topics in microbiology and immunology
#11
of 12 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 671 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,345 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.

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